A three-layered nano-carbonated hydroxyapatite/collagen/PLGA composite membrane for guided tissue regeneration

Liao, Susan; Wang, Wei; Uo, Motohiro; Ohkawa, Shoji; Akasaka, Tsukasa; Tamura, Kazuchika; Cui, Fuzhai; Watari, Fumio

doi:10.1016/j.biomaterials.2005.05.050

Cited by 252 publications

(168 citation statements)

References 30 publications

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“…32 This result was in good agreement with the SEM analysis. According to the rule of mixture, 33,34 if the bond between the constituents of a composite material is perfect, the strain in their constituents will be the same when a uniaxial tensile load is applied.…”

Section: Discussionsupporting

confidence: 87%

Three‐layered membranes of collagen/hydroxyapatite and chitosan for guided bone regeneration

et al. 2008

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The purpose of this study was to design a novel hybrid membrane with optimized properties for guided bone regeneration (GBR). Both the top and bottom layers of the sandwich-structured membrane were composed of collagen containing 20 wt% hydroxyapatite (HA), while the middle layer was made of chitosan. The above three layers were formulated into an integral membrane from their respective slurries through a layer-by-layer filtration process. The phase and composition of the membrane were confirmed by FT-IR and XRD analyses. The observation of its morphology by SEM showed that the membrane had a porous structure and structural integrity. The chitosan layer ensured the high tensile strength and elastic modulus of the membrane, while the presence of the collagen/HA composite layers endowed it with good flexibility and bioactivity. These results suggest that the integrated membrane prepared in this study would have the potential for use as a GBR material. '

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Section: Discussionsupporting

confidence: 87%

Three‐layered membranes of collagen/hydroxyapatite and chitosan for guided bone regeneration

et al. 2008

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“…The stressstrain curves of this biocomposite showed sufficient strength for medical application along with the relaxation of brittleness and fragility [448]. A three-layered graded biocomposite membrane, with one face of 8% nano-carbonated CDHA/collagen/PLGA porous membrane, the opposite face of pure PLGA non-porous membrane, the middle layer of 4% nano-carbonated CDHA/collagen/ PLGA as the transition, was prepared through the layer-bylayer casting method [512]. HA/glass FGM layers were coated on titanium alloy (Ti-6Al-4V) substrates.…”

Section: Functionally Graded Biocompositesmentioning

confidence: 99%

Calcium orthophosphate-based biocomposites and hybrid biomaterials

Dorozhkin¹

2009

J Mater Sci

283

146

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“…The works [71,72] describe orthopaedic implants made of hydroxyapatite and titanium. Bioactive hydroxyapatite is responsible for a strong connection with an organic tissue in such implants, whereas titanium is used in the parts of the implant requiring high mechanical stability.…”

Section: General Concept Of Sintered Gradient Materialsmentioning

confidence: 99%

Fabrication, Structure, Properties and Application of Gradient Sintered Carbide-Steels with HS6-5-2 Matrix

Dobrzański¹,

Kloc-Ptaszna²

2017

Powder Metallurgy - Fundamentals and Case Studies

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This chapter presents essential information concerning sintered tool materials containing carbides, i.e. high-speed steels and metal matrix composites, including sintered carbides and carbide steels. Gradient materials, whose properties change gradually according to their volume, are characterised. The results of investigations are presented in the final part into the structure and properties of newly developed sintered graded tool materials fabricated by the conventional metallurgy method from a mixture of high-speed HS6-5-2 steel powder and WC carbides. Investigations are described for four-layer materials, where the successive transition layers with a smaller and smaller volume fraction of tungsten carbide were constituted from the surface layer side, until a substrate layer containing high-speed HS6-5-2 steel only. The outcomes are described of structural examinations in a scanning and transmission electron microscope, an X-ray microanalysis and the results of density, porosity and hardness examinations of sintered gradient materials and the results of structure and hardness examinations of heat-treated materials.

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A three-layered nano-carbonated hydroxyapatite/collagen/PLGA composite membrane for guided tissue regeneration

Cited by 252 publications

References 30 publications

Three‐layered membranes of collagen/hydroxyapatite and chitosan for guided bone regeneration

Three‐layered membranes of collagen/hydroxyapatite and chitosan for guided bone regeneration

Calcium orthophosphate-based biocomposites and hybrid biomaterials

Fabrication, Structure, Properties and Application of Gradient Sintered Carbide-Steels with HS6-5-2 Matrix

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