A three‐field monoisocentric inverse breast treatment planning technique without half‐beam blocking

Zhang, Tiezhi; Dilworth, J.T.; Marina, Ovidiu; Chen, Peter; Benedetti, Lisa; Liu, Qiang

doi:10.1120/jacmp.v16i5.5494

Cited by 6 publications

(13 citation statements)

References 14 publications

(17 reference statements)

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“…Cunha et al . [ 19 ] used PC-ISO material to create a cylinder, resulting with better HU close to the water compared to our results (10 against 252), but the mechanical accuracy of our printed applicator was better comparing to their results, which was due to the differences between 3D printing technique accuracy. HU and density of printed material with FDM technique depend on choosing infill percentage.…”

Section: Discussioncontrasting

confidence: 57%

“…In order to select a material, biocompatibility, serializable and homogenic printing product, and water equivalency (specially for TPS with TG-43 algorithm) for brachytherapy need to be considered. Most of the studies used PA, PLA, ABS, and PC-ISO as a material with fused deposition modeling (known as FDM) technique [ 19 , 21 , 29 , 39 , 40 ]. Resin is yet another material with different sub-types, including rigid resin, tough resin, elastic resin, flexible resin, and high-temp resin for different purposes, with almost the same density.…”

Section: Discussionmentioning

confidence: 99%

“…We also used a method suggested and used by Cunha et al . [ 19 ] to evaluate the resin material. We have designed a couple L-shaped to hold Gafchromic film, as shown in Figure 5A, B .…”

Section: Methodsmentioning

confidence: 99%

“…Personalized vaginal applicators are one of the choices to overcome these limitations of commercially used vaginal applicators [ 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. Traditional technique, such as mold technique, is costly and time-consuming to create personalized vaginal applicator for each patient [ 23 ].…”

Section: Purposementioning

confidence: 99%

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Manufacturing and evaluation of multi-channel cylinder applicator with 3D printing technology

Mohammadi¹,

Siavashpour²,

Aghdam³

et al. 2021

jcb

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Purpose: This study was designed to assess dosimetric characteristics of 3D-printed personalized multi-channel cylinder applicator (MCCA). Material and methods: UnionTech RS Pro 600 (UnionTech, Inc., Shanghai, China) 3D printer was used for manufacturing MCCA. The geometry of MCCA was designed with Fusion 360 v.2.0.5827 (Autodesk, Inc.) software. The designed file was exported to Meshmixer v.3.5 (Autodesk, Inc.) to create three-dimensional model in stereolithography (STL) file format, which is the common file format for inputting data to 3D printers. We used high-temp resin, FLHTAM02 model (Formlabs Inc., MA, USA), as material in 3D printing process. This resin model has good resistance to high temperature and compatibility with various solvents. We created a simple cubic shape phantom for dosimetric evaluation of the applicator with Gafchromic EBT3 films. Also, Monte Carlo method was applied to simulate MCCA in the same configuration as in experimental test. Results: The mean ± standard deviation (SD) difference between measured and calculated doses in treatment planning system (TPS) for all control points was 0.0860 ±0.0393 Gy, corresponding to 4.01 ±1.21%. The mean ±SD difference between doses calculated by Monte Carlo simulation and TPS for all control points was 0.0996 ±0.0471 Gy, corresponding to 4.58 ±1.05%. The mean ±SD of dose difference between film measurement and Monte Carlo simulation for all control points was 0.0136 ±0.0200 Gy, corresponding to 0.60 ±0.69%. P-value for dose difference between film measurement and TPS, Monte Carlo and TPS, and film measurement and Monte Carlo were 0.7, 0.66, and 0.95, respectively. Conclusions: Dosimetric results and mechanical accuracy of MCCA show that high-temp resin with SLA 3D printing technique can be used for producing patient-specific MCCA in brachytherapy.

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Section: Discussioncontrasting

confidence: 57%

Section: Discussionmentioning

confidence: 99%

“…We also used a method suggested and used by Cunha et al . [ 19 ] to evaluate the resin material. We have designed a couple L-shaped to hold Gafchromic film, as shown in Figure 5A, B .…”

Section: Methodsmentioning

confidence: 99%

Section: Purposementioning

confidence: 99%

See 2 more Smart Citations

Manufacturing and evaluation of multi-channel cylinder applicator with 3D printing technology

Mohammadi¹,

Siavashpour²,

Aghdam³

et al. 2021

jcb

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“…Freehand needles can be used as well, but it is difficult to implant them accurately at predefined angels and to a certain location. However, only a limited number of reports on the use of 3D technology in BT have been published up to date [14,15,17,20,21,30,31]. For intact cervical cancer, CTV-T HR D 90 dose of ≥ 85 Gy in 7 weeks leads to 3-year local control rates of > 86% in large size CTV-T HR and > 93% in intermediate size CTV-T HR .…”

Section: Discussionmentioning

confidence: 99%

Development and assessment of 3D-printed individual applicators in gynecological MRI-guided brachytherapy

Logar¹,

Hudej²,

Šegedin³

2019

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Purpose: To evaluate the clinical use of 3D printing technology for the modelling of individual applicators for advanced gynecological tumors in magnetic resonance imaging (MRI)-based brachytherapy (BT). Material and methods: We tested individually designed 3D-printed applicators in nine patients with advanced gynecological cancer. Before BT was performed, all patients were treated with external beam radiotherapy (EBRT). The most common indication for individualized BT was advanced gynecological tumors where the use of standard BT applicators was not feasible. Other indications were suboptimal dose-volume histogram (DVH) parameters for high-risk clinical target volume (CTV-T HR) at the first BT (V 100 ≤ 90% of CTV-T HR volume and D 98 ≤ 80%, D 90 ≤ 100%, and D 100 ≤ 60% of dose aim). The EQD 2 dose aim to the target volume D 90 CTV-T HR per one BT fraction was 20 Gy for cervical or recurrent endometrial cancer and 16 Gy for vaginal cancer patient. The first BT with the standard applicator in situ was used as the virtual plan for designing a 3D-printed applicator. The next BT was performed with a 3D-printed applicator in situ. The primary endpoint was to improve CTV-T HR DVH parameters without exceeding the dose to the organs at risk (OARs). Results: All DVH parameters for CTV-T HR were significantly higher with the use of an individually designed applicator. Mean D 90 CTV-T HR improved from 14.1 ±5.4 Gy to 22.0 ±2.5 Gy and from 7.1 Gy to 16.2 Gy for cervical/recurrent endometrial and vaginal cancer, respectively (p < 0.001). The mean D 2cm 3 bladder, rectum, sigmoid, and bowel dose was within institutional dose constraints, and increased from 13.0 ±1.5 Gy to 13.6 ±1.5 Gy (p = 0.045), 10.8 ±1.2 Gy to 11.7 ±1.3 Gy (p = 0.004), 8.9 ±3.2 Gy to 10.3 ±3.3 Gy (p = 0.008), and 8.7 ±3.8 Gy to 9.2 ±3.1 Gy (p = 0.2). Conclusions: With the use of individual 3D-printed applicators, all DVH parameters for CTV-T HR significantly improved without compromising the dose constraints for the OARs.

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Validation of the geometric equivalent field concept in total scatter factor calculations, for half‐, quarter‐ and off‐isocenter asymmetric square fields

Hmodi,

Nahili,

Tsalafoutas

et al. 2023

J Applied Clin Med Phys

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ObjectiveMonitor unit (MU) verification for any symmetric or asymmetric field is performed using a total scatter factor (Scp), that is calculated based on the geometric equivalent square field (GESF) concept. In this study, we measured the Scp of various asymmetric square fields (ASFs) and their respective GESFs.MethodsSquare half‐fields (SHFs), square quarter‐fields (SQFs) and square off‐isocenter fields (SOFs), with sizes ranging from 3×3 cm2 to 20×20 cm2 were created, by varying the collimator jaws of two Varian iX Linacs (6/18 and 6/23 MV). A semi‐flex ion chamber was used to measure Scp at a depth of 10 cm within a water phantom, at the effective field center (EFC) of all ASFs, and at the isocenter (IC) of their respective GESFs. The later Scp values were corrected by the off‐axis ratio [OAR(r)] of the 40×40 cm2 field size, where r is the distance between EFC and IC.ResultsThe results show that the Scp (EFC) is independent of the type of the ASF (SHF, SQF, or SOF) and no significant difference exists between the 18 and 23 MV beams. Compared with the Scp (IC), the Scp (EFC) increased with increasing r, by up to 2% and 4% for 18/23 and 6 MV, respectively.ConclusionsThe GESF concept provides acceptable accuracy (< 2%) for the calculation of Scp of the ASFs used in most clinical situations (except from SOF with EFC at large r), and thus can be used in MU verification calculations.

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A three‐field monoisocentric inverse breast treatment planning technique without half‐beam blocking

Cited by 6 publications

References 14 publications

Manufacturing and evaluation of multi-channel cylinder applicator with 3D printing technology

Manufacturing and evaluation of multi-channel cylinder applicator with 3D printing technology

Development and assessment of 3D-printed individual applicators in gynecological MRI-guided brachytherapy

Validation of the geometric equivalent field concept in total scatter factor calculations, for half‐, quarter‐ and off‐isocenter asymmetric square fields

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