A tension offloading patch mitigates dermal fibrosis induced by pro-fibrotic skin injections
Derrick Wan,
Heather Talbott,
Michelle Griffin
et al.
Abstract:Skin fibrosis is a clinical problem with devastating impacts but limited treatment options. In the setting of diabetes, insulin administration often causes local dermal fibrosis, leading to a range of clinical sequelae including impeded insulin absorption. Mechanical forces are important drivers of fibrosis and, clinically, physical tension offloading at the skin level using an elastomeric patch significantly reduces wound scarring. However, it is not known whether tension offloading could similarly prevent sk… Show more
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