Recently, increased stress and turnover tendency among female healthcare workers due to work-family imbalance have become key issues affecting the sustainable and healthy development of the healthcare system. It is warranted to explore the network relationships between work-family balance, perceived stress and turnover intentions to target the turnover of female healthcare workers. The Work-Family Balance Scale, the Perceived Stress Scale and the Turnover Intentions Scale were used to survey 436 female healthcare workers, and network analysis of the data via R software. The network analysis showed that turnover intentions had strong connections with perceived stress, adjustment, defense and conversion, while feeble connections with feedback and compensation (controlling for age, marital status and child-rearing). This suggested the degree of work impact, intrusion, or conflict on the family was the key factor influencing the level of stress and turnover intention in female medical professionals, with less consideration given to whether employment might contribute resources to the family.