A TBET based BODIPY-rhodamine dyad for the ratiometric detection of trivalent metal ions and its application in live cell imaging

A simple hydrazone as a multianalyte (Cu2+, Al3+, Zn2+) sensor at different pH values and the resultant Al3+ complex as a sensor for F−

“…8,9 Besides, the detection of Al 3+ can be easily interfered with by the matrix, leading to limited selectivity and sensitivity. [10][11][12] Thus, designing a selective and sensitive uorescence probe for Al 3+ in aqueous media remains a challenge.…”

Polypyridyl substituted BODIPY derivatives; water switchable imaging probes that exhibit halogen substituent dependent localisation in live cells

“…Unhalogenated BODIPY compounds employed previously as cellular contrast agents have been shown to localise in the lysosomes of HeLa cells 25,53 and cytoplasm of a range of other cell lines but have similarly largely been nuclear excluding. 5,25,27,33,36,40,59 Far less has been reported on uptake and particularly distribution of halogenated BODIPY derivatives in live cells to date. 18 It is important to note that while DMSO was used to solubilise the compounds prior to addition to the cells the nal concentration of DMSO in the medium was 0.1% v/v.…”

“…Finally, BODIPY derivatives with appended coordination sites have been widely studied as sensors for transduction of metal ion binding reported through uorescence. [5][6][7]11,12,19,24,25,[31][32][33][34][35][37][38][39][40][41][42][43][44][45][46] We have also recently shown that complexation of a ruthenium metal centre to a polypyridylbased BODIPY uorophore does not alter BODIPY emission permitting the use of the complex as a ratiometric oxygen sensor. 35 As the reported BODIPY derivatives are functionalised at the meso-position with metal coordinating ligands, we report a preliminary investigation into their ability to complex biologically relevant metal ions in non-aqueous media and the effect of metal binding on photophysical properties of the dyes.…”

Portable Multispectral Colorimeter for Metallic Ion Detection and Classification

“…The dyad biodipy–rhodamine molecule was utilized for three-valent ions (Al(III), Cr(III), Fe(III)) detection by monitoring changes in fluorescence emission due to energy transfer from biodipy to rhodamine moiety, this dyad molecule did not show any selectivity between these ions, as was reported. The dyad could also be manipulated as an imaging indicator in the biological cell culture [ 8 ]. A carbon dot ending with carboxylate groups was applied as a chemo sensor for the detection of many metallic ions, by using the photoluminescence quenching of these dots.…”