Abstract:The chemo-photothermal cotherapy has created a breakthrough in cancer treatment, but the precise delivery of drugs to tumor sites and the thermoresistance of tumors remain major challenges in photothermal therapy (PTT). Due to its overexpression in small cell lung cancer (SCLC) and limited normal tissue expression, Somatostatin receptor 2 (SSTR2) is proposed as an ideal target for the precise treatment of SCLC. We first developed a novel anti-SSTR2 monoclonal antibody (MAb), which showed strong and specific af… Show more
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