A Targeted Approach for the Metabolome Analysis of E. coli Biofilms
Jan Rockstroh,
Sandy Gerschler,
Nadin Schultze
et al.
Abstract:Biofilms of pathogenic bacteria are responsible for persistent infections in humans, therefore investigations of biofilm formation and treatment strategies are required. The gram‐negative enterobacterium Escherichia (E.) coli is the most common pathogen causing chronic or recurring urinary tract infections. Metabolomics approaches targeted the bacterium to investigate specific metabolic patterns of biofilms and regulatory influences on biofilm formation. In this study, we aimed to investigate the metabolome of… Show more
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