A systematic review on the efficacy, safety and types of Chinese herbal medicine for depression

Yeung, Wing‐Fai; Chung, Ka Fai; Ng, Ka Yan; Yu, Branda Yee Man; Ziea, Eric; Ng, Bacon Fung Leung

doi:10.1016/j.jpsychires.2014.05.016

Cited by 81 publications

(59 citation statements)

References 29 publications

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“…[30][31][32][33][34][35][36][37][38][39][40][41][42][43][44] Thirty-one additional systematic reviews formally met eligibility criteria, but their content was superseded by at least one of the 19 reviews mentioned above (online supplementary file 4). figure 1 presents the flow of the literature; table 2 presents characteristics of included reviews.…”

Section: Strength Of the Evidencementioning

confidence: 99%

“…30 31 44 We used response to treatment as defined by authors of the reviews; in most cases, this was a 50% reduction of symptoms as measured on a depression rating scale (eg, Hamilton Depression Rating Scale). figure 4 depicts the absolute risk reductions or increases for response to treatment per 1000 patients.…”

Section: Non-pharmacological Treatments Compared With Second-generatimentioning

confidence: 99%

“…Three systematic reviews reported on comparisons with second-generation antidepressants for seven (of 56 30 31 44 Except for omega-3 fatty acids, none of the comparisons yielded statistically significant differences. Based on results of a network meta-analysis, patients using omega-3 fatty acids were statistically significantly less likely to achieve response than patients on antidepressants (RR 0.51; 95% CI 0.33 to 0.79).…”

Section: Cam Interventionsmentioning

confidence: 99%

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Pharmacological and non-pharmacological treatments for major depressive disorder: review of systematic reviews

et al. 2017

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ObjectivesThis study aims to summarise the evidence on more than 140 pharmacological and non-pharmacological treatment options for major depressive disorder (MDD) and to evaluate the confidence that patients and clinicians can have in the underlying science about their effects.DesignThis is a review of systematic reviews.Data sourcesThis study used MEDLINE, Embase, Cochrane Library, PsycINFO and Epistemonikos from 2011 up to February 2017 for systematic reviews of randomised controlled trials in adult patients with acute-phase MDD.MethodsWe dually reviewed abstracts and full-text articles, rated the risk of bias of eligible systematic reviews and graded the strength of evidence.ResultsNineteen systematic reviews provided data on 28 comparisons of interest. For general efficacy, only second-generation antidepressants were supported with high strength evidence, presenting small beneficial treatment effects (standardised mean difference: −0.35; 95% CI −0.31 to −0.38), and a statistically significantly higher rate of discontinuation because of adverse events than patients on placebo (relative risk (RR) 1.88; 95% CI 1.0 to 3.28).Only cognitive behavioural therapy is supported by reliable evidence (moderate strength of evidence) to produce responses to treatment similar to those of second-generation antidepressants (45.5% vs 44.2%; RR 1.10; 95% CI 0.93 to 1.30). All remaining comparisons of non-pharmacological treatments with second-generation antidepressants either led to inconclusive results or had substantial methodological shortcomings (low or insufficient strength of evidence).ConclusionsIn contrast to pharmacological treatments, the majority of non-pharmacological interventions for treating patients with MDD are not evidence based. For patients with strong preferences against pharmacological treatments, clinicians should focus on therapies that have been compared directly with antidepressants.Trial registration numberInternational Prospective Register of Systematic Reviews (PROSPERO) registration number: 42016035580.

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Section: Strength Of the Evidencementioning

confidence: 99%

Section: Non-pharmacological Treatments Compared With Second-generatimentioning

confidence: 99%

Section: Cam Interventionsmentioning

confidence: 99%

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Pharmacological and non-pharmacological treatments for major depressive disorder: review of systematic reviews

et al. 2017

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“…For some natural additives, there is little possibility of industrial application because they are less economic and more inefficient compared with synthetic additives [8,9]. However, herbal medicines have long been regarded as widely available and are potential sources of natural additives [10,11,12]. Traditionally, herbal medicines have been used in the treatment and prevention of diseases, and as raw food material in East Asia [10,13].…”

Section: Introductionmentioning

confidence: 99%

Effect of Various Herbal Medicine Extracts on the Physico-chemical Properties of Emulsion-type Pork Sausage

Jin¹,

Ha²,

Hur³

et al. 2015

JFNR

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The purpose of this study was to evaluate the functional properties of herbal medicine aqueous extracts as natural preservatives to improve the quality characteristics and oxidative stability of emulsion-type pork sausage. The pH value was significantly higher in sausages of control than in groups containing herbal medicine extracts (p<0.05). The shear force values increased with the addition of herbal medicine extracts (p<0.05). The addition of herbal medicine extracts also reduced the lightness and redness, and increased the yellowness, chroma, and hue observed during storage (p<0.05). In addition, the anti-oxidative activity including 2-thiobarbituric acid reactive substances (TBARS), peroxide value (POV), and 2,2-diphenyl-1-picryhydrazla hydrate (DPPH) was higher in the Akebiaquinata (T3), Lonicera japonica (T4), and Chelidoniummajus (T5) groups than in the other groups (p<0.05). In a sensory evaluation, the Liriopeplatyphylla (T1) and Saposhnikoviaedivaricata (T2) groups scored lower than the control, whereas the T3, T4, and T5 groups showed similar attributes compared with the control. In conclusion, the addition of herbal medicine extracts did not have negative effects on the quality of emulsion-type pork sausage, and they could be used as a natural antioxidant material to prevent lipid oxidation in meat products.

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“…Another clinical trial demonstrated that the two most commonly prescribed CHPs for patients with insomnia were Jia-Wei-Xiao-Yao-San and SuanZao-Ren-Tang, both effectively improving sleep quality (Wu et al, 2011;Yeh et al, 2011). A systematic review on the efficacy, safety and types of Chinese herbal medicine for depression has concluded that CHM including Chai-Hu-Chia-Lung-Ku-Mu-Li-Tang and Jia-Wei-Xiao-Yao-San was more effective than placebo and as effective as antidepressants in the treatment of depression (Yeung et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

Prescription patterns of Chinese herbal products for patients with sleep disorder and major depressive disorder in Taiwan

Chen

Lee

Huang

et al. 2015

Journal of Ethnopharmacology

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A systematic review on the efficacy, safety and types of Chinese herbal medicine for depression

Cited by 81 publications

References 29 publications

Pharmacological and non-pharmacological treatments for major depressive disorder: review of systematic reviews

Pharmacological and non-pharmacological treatments for major depressive disorder: review of systematic reviews

Effect of Various Herbal Medicine Extracts on the Physico-chemical Properties of Emulsion-type Pork Sausage

Prescription patterns of Chinese herbal products for patients with sleep disorder and major depressive disorder in Taiwan

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