A systematic review on physical function, activities of daily living and health-related quality of life in COVID-19 survivors

Almeida, Katna de Oliveira; Alves, Iura Gonzalez Nogueira; Queiroz, Rodrigo Santos de; Castro, Marcela Rodrigues de; Gomes, Vinícius Afonso; Fontoura, Fabiane Costa Santos; Brites, Carlos; Neto, Mansueto Gomes

doi:10.1177/17423953221089309

Cited by 54 publications

(49 citation statements)

References 68 publications

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“…However, to our knowledge, our study is one of the first reports of one-year follow-ups of patients who survived COVID-19 in Latin America and low- and middle-income countries [ 55 ]. Moreover, these countries had limited access to mental healthcare, which worsened during the pandemic [ 56 ], and they cannot fully extrapolate most technology-based interventions [ 57 ].…”

Section: Discussionmentioning

confidence: 99%

One-year follow-up of depression, anxiety, and quality of life of Peruvian patients who survived COVID-19

et al. 2022

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Purpose To assess health-related quality of life (HRQoL) and its associated factors in patients who survived COVID-19 and to assess a prospective evaluation of the prevalence and severity of their depression and anxiety symptoms. Methods We followed up a sample of hospitalized patients who survived COVID-19 at 3 and 12 months after discharge. We assessed HRQoL (Euroqol-5D-5L) through telephone interviews. Any problem in any dimension of Euroqol-5D-5L was considered as low HRQoL. The depression and anxiety symptoms were measured using the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 tools, respectively. We estimated the adjusted prevalence ratios (aPR) to low HRQoL using Poisson regression and the changes on their depression and anxiety symptoms during the follow-up. Results We included 119 patients with a mean follow-up time of 363.6 days. 74% of the participants had low HRQoL at one year after hospital discharge and were associated with being ≥ 41 years old (aPR: 1.95), having a previous history of psychiatric diagnoses before COVID-19 infection (aPR: 1.47), having any COVID-19 symptom during the follow-up at one year (aPR: 1.84), and having a family member who had died from COVID-19 during the first wave (aPR: 1.24). In addition, the clinically relevant depression symptoms were frequent, and they increased from 3 (14.3%) to 12 months (18.5%). Conclusion One year after COVID-19 hospitalization discharge, patients had low HRQoL, and their depression symptoms increased. These findings acknowledge the need to provide services that adequately address mental health sequels and HRQoL to reduce the burden of the COVID-19.

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Section: Discussionmentioning

confidence: 99%

One-year follow-up of depression, anxiety, and quality of life of Peruvian patients who survived COVID-19

et al. 2022

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“…In this context, despite the fact that the definition of hypogonadism usually applied in the literature refers to an established testosterone deficiency condition (i.e., late onset hypogonadism considered as a chronic condition), using the wording of ‘suggestive for biochemical hypogonadism’ is more scientifically accurate. Fifth, our data did not allow to study yet a potential correlation between circulating tT over time and the so‐called long‐COVID syndrome 24,25 . Likewise, our data did not allow to investigate a potential correlation between circulating tT both at baseline and over time and the impact of the new variants of SARS‐CoV‐2, which had emerged over the last a few months 26 …”

Section: Discussionmentioning

confidence: 89%

Testosterone in males with COVID‐19: a 12‐month cohort study

et al. 2022

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Background: Circulating testosterone levels have been found to be reduced in men with severe acute respiratory syndrome coronavirus 2 infection, COVID-19, with lower levels being associated with more severe clinical outcomes. Objectives:We aimed to assess total testosterone levels and the prevalence of total testosterone still suggesting for hypogonadism at 7-month follow-up in a cohort of 121 men who recovered from laboratory-confirmed COVID-19.Materials and methods: Demographic, clinical, and hormonal values were collected for all patients. Hypogonadism was defined as total testosterone ≤9.2 nmol/L. The Charlson Comorbidity Index was used to score health-significant comorbidities. Descriptive statistics and multivariable linear and logistic regression models tested the association between clinical and laboratory variables and total testosterone levels at follow-up assessment.

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“…In COVID-19, central, psychological, and peripheral factors have been suggested to be involved in the pathophysiology of fatigue 50 . Due to the multifactorial aspect and impact on ADLs 51 , we used the PFSDQ-M 29 to assess this outcome in our study.…”

Section: Fatigue and Dyspneamentioning

confidence: 99%

Rehabilitation in Survivors of COVID-19 (RE2SCUE): a non-randomized, controlled and open study

Campos

Nery

Speck

et al. 2022

Preprint

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The sequelae of coronavirus disease-2019 (COVID-19) are another socio-economic problem of the pandemic. Fatigue and dyspnea are the most prevalent symptoms. It is not known whether exercise can be used to treat long COVID-19. This study aimed to investigate the effects of an 8-week face-to-face rehabilitation program on COVID-19 compared to a remote monitoring group. A total of 37 participants (24.3% hospitalized) were assessed before and after rehabilitation (n = 22; 40.8 ± 10.0 years) or remote monitoring (n = 15; 45.4 ± 10.5 years). The participants were allocated according to their preferences. Both groups showed improved fatigue and exercise capacity (Incremental Shuttle Walk Test). Participants in the face-to-face rehabilitation group showed improved dyspnea (Pulmonary Functional Status and Dyspnea Questionnaire), anxiety (Hospital Anxiety and Depression Scale), attention, and short-term memory (d2-R and Rey's Auditory-Verbal Learning Test). Of the main sequelae, fatigue improves naturally, whereas dyspnea requires rehabilitation. Our results demonstrated the benefits of exercise for COVID-19 sequelae.

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A systematic review on physical function, activities of daily living and health-related quality of life in COVID-19 survivors

Cited by 54 publications

References 68 publications

One-year follow-up of depression, anxiety, and quality of life of Peruvian patients who survived COVID-19

One-year follow-up of depression, anxiety, and quality of life of Peruvian patients who survived COVID-19

Testosterone in males with COVID‐19: a 12‐month cohort study

Rehabilitation in Survivors of COVID-19 (RE2SCUE): a non-randomized, controlled and open study

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