A systematic review of the psychobiological burden of informal caregiving for patients with dementia: Focus on cognitive and biological markers of chronic stress

Allen, Andrew P.; Curran, Eileen A.; Duggan, Áine; Cryan, John F.; Chorcoráin, Aoife Ní; Dinan, Timothy G.; Molloy, D. William; Kearney, Patricia M.; Clarke, Gerard

doi:10.1016/j.neubiorev.2016.12.006

Cited by 195 publications

(160 citation statements)

References 187 publications

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“…Previous reviews have found an association between perceived caregiver burden and informal care due to the hours involved in care, stress, depression, anxiety, social isolation and lack of social resources (Allen et al, 2017;Chiao, Wu, & Hsiao, 2015;Ornstein & Gaugler, 2012;Sansoni, Anderson, Varona, & Varela, 2013). Assuming a role as caregivers, spouses often experience grief and multiple losses, including loss of partner and personal freedom (Chan, Livingston, Jones, & Sampson, 2013).…”

Section: Introductionmentioning

confidence: 99%

Living with a partner with dementia: a systematic review and thematic synthesis of spouses' lived experiences of changes in their everyday lives

Egilstrød

Ravn

Petersen

2018

Aging & Mental Health

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Objectives: Dementia causes dramatic changes in everyday-living for spouses. Occured changes in marital relationship, force spouses to perform more both mentally and physically. Leading to a spousal perceived burden. To improve understanding of spouses' needs, spouses lived experiences is needed. The aim was to identify and synthesise qualitative studies on spouses' lived experiences of living with a partner with dementia. Methods: A systematic search was undertaken in January 2017. Six databases (CINAHL, Cochrane Library, Embase, PubMed, PsycINFO and Sociological Abstracts) were searched, using search terms in accordance with PICo. A descriptive synthesis and a thematic synthesis were undertaken. Findings: Fifteen studies met the inclusion criteria. Three themes derived from the analysis 1) Noticing changes in everyday life 2) Transformation to a new marital relation in everyday life, with corresponding sub-themes; changes in marital relationship, management of the transitioned marital relation in everyday life 3) Planning the future. Conclusion: Findings provide an overview of how spouses notice changes and transform their marital relationships in everyday-life. Findings offer a deeper understanding of changes that occurs over time while the partner is living at home. Findings contribute with knowledge on spouses' experiences of changes in early-stages of dementia. Interventions supporting spouses are needed.

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Section: Introductionmentioning

confidence: 99%

Living with a partner with dementia: a systematic review and thematic synthesis of spouses' lived experiences of changes in their everyday lives

Egilstrød

Ravn

Petersen

2018

Aging & Mental Health

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“…Research indicates that the gut microbiota is associated with health in the elderly, with those in long‐term care having a less diverse microbiota than those living in the community (Claesson et al, ), although there is substantial distinctiveness at an interindividual level (Claesson et al, ). Even under conditions of healthy ageing, there can be a decline in some aspects of cognition (e.g., Koen & Yonelinas, ), but given the rising global health burden of dementia (Prince et al, ), as well as the psychological and physiological toll this can take upon caregivers (e.g., Allen, Curran et al, ; Etters, Goodall, & Harrison, ; Kiecolt‐Glaser, Dura, Speicher, Trask, & Glaser, ) a greater understanding of how gut health may impact upon the psychological health in ageing is critical. Despite this initial interest in gut microbiota changes with advancing age, there has been a relative lack of long‐term longitudinal research examining changes in the human gut microbiota.…”

Section: The Gut Microbiota and Psychological Developmentmentioning

confidence: 99%

A psychology of the human brain–gut–microbiome axis

Allen

Dinan

Clarke

et al. 2017

Social & Personality Psych

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130

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In recent years, we have seen increasing research within neuroscience and biopsychology on the interactions between the brain, the gastrointestinal tract, the bacteria within the gastrointestinal tract, and the bidirectional relationship between these systems: the brain–gut–microbiome axis. Although research has demonstrated that the gut microbiota can impact upon cognition and a variety of stress‐related behaviours, including those relevant to anxiety and depression, we still do not know how this occurs. A deeper understanding of how psychological development as well as social and cultural factors impact upon the brain–gut–microbiome axis will contextualise the role of the axis in humans and inform psychological interventions that improve health within the brain–gut–microbiome axis. Interventions ostensibly aimed at ameliorating disorders in one part of the brain–gut–microbiome axis (e.g., psychotherapy for depression) may nonetheless impact upon other parts of the axis (e.g., microbiome composition and function), and functional gastrointestinal disorders such as irritable bowel syndrome represent a disorder of the axis, rather than an isolated problem either of psychology or of gastrointestinal function. The discipline of psychology needs to be cognisant of these interactions and can help to inform the future research agenda in this emerging field of research. In this review, we outline the role psychology has to play in understanding the brain–gut–microbiome axis, with a focus on human psychology and the use of research in laboratory animals to model human psychology.

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“…Family caregivers also score worse than others on tests of attention and on executive functions such as planning, cognitive flexibility and abstract thinking. Interventions aimed at reducing family caregivers' stress levels have, to varying degrees, led to a reduction in cortisol levels (Allen et al, 2017).…”

Section: Family Caregivers Of People With Dementiamentioning

confidence: 99%

The influence of day care centres for people with dementia on family caregivers: an integrative review of the literature

Tretteteig

Vatne

Rokstad

2015

Aging & Mental Health

104

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A systematic review of the psychobiological burden of informal caregiving for patients with dementia: Focus on cognitive and biological markers of chronic stress

Cited by 195 publications

References 187 publications

Living with a partner with dementia: a systematic review and thematic synthesis of spouses' lived experiences of changes in their everyday lives

Living with a partner with dementia: a systematic review and thematic synthesis of spouses' lived experiences of changes in their everyday lives

A psychology of the human brain–gut–microbiome axis

The influence of day care centres for people with dementia on family caregivers: an integrative review of the literature

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