A systematic review of the exercise effects on burn wound healing

Niumanlan,; Jingming, Yan; Hao, Qin; Farzan, Ramyar; Alizadeh Otaghvar, Hamidreza

doi:10.1111/iwj.14482

Cited by 3 publications

(1 citation statement)

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“…Burn injuries can have both profound physical and emotional impacts, often giving rise to a range of psychological challenges, with anxiety being a prominent issue. 69,[87][88][89][90][91][92][93][94][95][96][97]101 The emotional weight of this condition can significantly influence the overall health and recuperation of individuals recovering from burn injuries. It is essential to grasp the extent of anxiety prevalence and the factors linked to it in burn patients to ensure they receive comprehensive care.…”

Section: Highmentioning

confidence: 99%

Prevalence of anxiety and its risk factors in burn patients: A systematic review and meta‐analysis

Zaboli Mahdiabadi,

Farhadi,

Shahroudi

et al. 2024

International Wound Journal

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The primary objective of this systematic review and meta‐analysis was to ascertain the prevalence of anxiety and identify associated risk factors among individuals who have suffered burn injuries. We conducted a thorough and systematic search across various international electronic databases, including Scopus, PubMed and Web of Science, as well as Persian electronic databases like Iranmedex and the scientific information database (SID). Our search encompassed the period from the earliest available records up to 8 August 2023. We employed keywords derived from Medical Subject Headings (MeSH) such as “Prevalence”, “Anxiety” and “Burns”. In total, 2586 burn patients participated in 13 cross‐sectional studies. The mean age of the participants was 32.88 (SD = 2.51). In a compilation of 13 studies, the documented overall occurrence rate of anxiety among burn patients stood at 16.1% (95% CI: 10.0% to 24.7%; I2 = 93.138%; p < 0.001). The outcomes of a meta‐regression analysis, which examined the association between anxiety in burn patients and the year of publication, did not uncover any significant correlation (p = 0.442). Furthermore, there was a notable association between anxiety in burn patients and factors such as gender, TBSA affected, educational level and the types of burn injuries. Therefore, healthcare providers need to recognize the substantial prevalence of anxiety in burn patients as a fundamental consideration. This recognition should prompt a proactive approach toward early detection and timely intervention. Developing personalized intervention strategies tailored to each patient's unique risk factors and needs is paramount. These strategies may encompass a range of therapeutic options such as counselling, psychotherapy or consultations with mental health specialists.

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Section: Highmentioning

confidence: 99%

Prevalence of anxiety and its risk factors in burn patients: A systematic review and meta‐analysis

Zaboli Mahdiabadi,

Farhadi,

Shahroudi

et al. 2024

International Wound Journal

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Prediction of immune molecules activity during burn wound healing among elderly patients: in-silico analyses: experimental research

Zabihi,

Akhoondian,

Tamimi

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction: Burn injuries lead to dysregulation of immune molecules, impacting cellular and humoral immune pathways. This study aims to determine the prediction of immune molecules activity during burn wound healing among elderly patients. Methods: The current study utilized the Gene Expression Omnibus (GEO) database to extract the proper gene set. Also, the literature review was conducted in the present study to find immune signatures. The study used the “enrich r” website to identify the biological functions of extracted genes. The critical gene modules related to mortality were identified using the weighted gene co-expression network analysis (WGCNA) R package. Results: The appreciated GSE was extracted. According to the data, the most upregulated signatures were related to Natural Killer (NK) Cells, and the most downregulated signatures were associated with M1 macrophages. Also, The results of WGCNA have shown that the most related gene modules (P<107 and score 0.17) to mortality were investigated, and the modules 100 first genes were extracted. Additionally, the enrich r analysis has demonstrated related pathways, including; the immune process, including regulation of histamine secreted from mast cell (P<0.05), T helper 17 cell differentiation (P<0.05), and autophagy (P<0.05) were obtained. Finally, by network analysis, the critical gene “B3GNT5” were obtained (degree>ten and “betweenness and centrality”>30 were considered). Conclusion: The study identified significant changes in macrophage and NK cell expression patterns post-burn injury, linking them to potential improvements in clinical outcomes and wound healing. The gene B3GNT5, associated with mortality, was highlighted as a key marker for prognostic evaluation.

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Lifestyle Medicine Approach to Wound Management

Lai

2024

American Journal of Lifestyle Medicine

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Chronic wounds impact 4.5% of the US population, necessitating a comprehensive understanding of their types and underlying mechanisms. Diabetic foot ulcers (DFUs), prevalent in 25% of individuals with diabetes, contribute significantly to lower limb amputations. The pathophysiology involves neuropathy, peripheral arterial disease, impaired immunity, glycemic control, and mechanical stress. Lifestyle medicine emerges as a pivotal aspect of care, offering both prevention and treatment by integrating plant-predominant nutrition, physical activity, stress management, avoidance of harmful substances, restful sleep, and social connectedness. These interventions impact gene interactions, immune function, and tissue regeneration, playing a crucial role in chronic wound management. The standard of care involves a multidisciplinary approach, emphasizing infection and vascular management, pressure offloading, conducive wound healing environments, and lifestyle adjustments. As diabetes prevalence rises, a proactive integration of lifestyle interventions is crucial, offering a promising avenue to alleviate the growing healthcare burden associated with chronic wounds.

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A systematic review of the exercise effects on burn wound healing

Cited by 3 publications

References 102 publications

Prevalence of anxiety and its risk factors in burn patients: A systematic review and meta‐analysis

Prevalence of anxiety and its risk factors in burn patients: A systematic review and meta‐analysis

Prediction of immune molecules activity during burn wound healing among elderly patients: in-silico analyses: experimental research

Lifestyle Medicine Approach to Wound Management

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