A Systematic Review of Quality of Life and Sexual Function of Patients With Cervical Cancer After Treatment

Ye, Shuang; Yang, Jiaxin; Cao, Dongyan; Lang, Jinghe; Shen, Keng

doi:10.1097/igc.0000000000000207

Cited by 97 publications

(49 citation statements)

References 49 publications

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“…Given that radiation therapy damages the vaginal epithelium [38], pathogenic bacteria may be able to cross the epithelium and cause chronic inflammation that contributes to vaginal atrophy. Vaginal atrophy contributes to sexual dysfunction, which is known to affect QOL post-treatment [39].…”

Section: Therapy-induced Symptomsmentioning

confidence: 99%

The vaginal and gastrointestinal microbiomes in gynecologic cancers: A review of applications in etiology, symptoms and treatment

Chase

Goulder

Zenhausern

et al. 2015

Gynecologic Oncology

114

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Section: Therapy-induced Symptomsmentioning

confidence: 99%

The vaginal and gastrointestinal microbiomes in gynecologic cancers: A review of applications in etiology, symptoms and treatment

Chase

Goulder

Zenhausern

et al. 2015

Gynecologic Oncology

114

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“…One review identified 30 self-reported measures of sexual function used in quantitative studies in women with breast cancer (Bartula & Sherman, 2013), while another identified eight measures used in women with cervical cancer (Ye, Yang, Cao, Lang, & Shen, 2014). The large number of sexual function measures suggests interest in this quality of life domain, but also creates a quandary in the selection of measures appropriate for oncology settings.…”

Section: Introductionmentioning

confidence: 99%

Self-Reported Sexual Function Measures Administered to Female Cancer Patients: A Systematic Review, 2008–2014

Jeffery¹,

Barbera

Andersen

et al. 2015

Journal of Psychosocial Oncology

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Background A systematic review was conducted to identify and characterize self-reported sexual function (SF) measures administered to women with a history of cancer. Methods Using 2009 PRISMA guidelines, we searched electronic bibliographic databases for quantitative studies published January 2008–September 2014 that used a self-reported measure of SF, or a quality of life (QOL) measure that contained at least one item pertaining to SF. Results Of 1,487 articles initially identified, 171 were retained. The studies originated in 36 different countries with 23% from U.S.-based authors. Most studies focused on women treated for breast, gynecologic, or colorectal cancer. About 70% of the articles examined SF as the primary focus; the remaining examined QOL, menopausal symptoms, or compared treatment modalities. We identified 37 measures that assessed at least one domain of SF, eight of which were dedicated SF measures developed with cancer patients. Almost one-third of the studies used EORTC QLQ modules to assess SF, and another third used the Female Sexual Function Inventory. There were few commonalities among studies, though nearly all demonstrated worse SF after cancer treatment or compared to healthy controls. Conclusions QOL measures are better suited to screening while dedicated SF questionnaires provide data for more in depth assessment. This systematic review will assist oncology clinicians and researchers in their selection of measures of SF and encourage integration of this quality of life domain in patient care.

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“…Although still poorly addressed in the literature, vaginal shortening seems a significant complication of the surgical treatment of cervix and/or vaginal neoplasia and is a source of dyspareunia or dehiscence [1,2]. However, the specific sexual impact of this situation is variable according to the patient and her partner [3].…”

Section: Discussionmentioning

confidence: 99%

A Simple Laparoscopic Procedure to Restore a Normal Vaginal Length After Colpohysterectomy With Large Upper Colpectomy for Cervical and/or Vaginal Neoplasia

Leblanc

Bresson

Merlot

et al. 2016

Journal of Minimally Invasive Gynecology

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Colpohysterectomy is sometimes associated with a large upper colpectomy resulting in a shortened vagina, potentially impacting sexual function. We report on a preliminary experience of a laparoscopic colpoplasty to restore a normal vaginal length. Patients with shortened vaginas after a laparoscopic colpohysterectomy were considered for a laparoscopic modified Davydov's procedure to create a new vaginal vault using the peritoneum of the rectum and bladder. From 2010 to 2014, 8 patients were offered this procedure, after informed preoperative consent. Indications were 2 extensive recurrent vaginal intraepithelial neoplasias grade 3 and 6 radical hysterectomies for cervical cancer. Mean vaginal length before surgery was 3.8 cm (standard deviation, 1.6). Median operative time was 50 minutes (range, 45-90). Blood loss was minimal (50-100 mL). No perioperative complications occurred. Median vaginal length at discharge was 11.3 cm (range, 9-13). Sexual intercourse could be resumed around 10 weeks after surgery. At a median follow-up of 33.8 months (range, 2.4-51.3), 6 patients remained sexually active but 2 had stopped. Although this experience is small, this laparoscopic modified Davydov's procedure seems to be an effective procedure, adaptable to each patient's anatomy. If the initial postoperative regular self-dilatation is carefully observed, vaginal patency is durably restored and enables normal sexual function.

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A Systematic Review of Quality of Life and Sexual Function of Patients With Cervical Cancer After Treatment

Abstract: The studies showed that QoL and sexual function in CCSs were compromised compared with the general population to different extents. Quality of life and sexual function should be paid with more attention in patients with cervical cancer after treatment.

Cited by 97 publications

References 49 publications

The vaginal and gastrointestinal microbiomes in gynecologic cancers: A review of applications in etiology, symptoms and treatment

The vaginal and gastrointestinal microbiomes in gynecologic cancers: A review of applications in etiology, symptoms and treatment

Self-Reported Sexual Function Measures Administered to Female Cancer Patients: A Systematic Review, 2008–2014

A Simple Laparoscopic Procedure to Restore a Normal Vaginal Length After Colpohysterectomy With Large Upper Colpectomy for Cervical and/or Vaginal Neoplasia

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