A systematic review of qualitative research on the contributory factors leading to medicine-related problems from the perspectives of adult patients with cardiovascular diseases and diabetes mellitus

Hamid, Abdullah Al; Ghaleb, Maisoon; Aljadhey, Hisham; Aslanpour, Zoe

doi:10.1136/bmjopen-2014-005992

Cited by 31 publications

(32 citation statements)

References 33 publications

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“…This would be beneficial because medication adherence is one of the most crucial factors contributing to the therapy's success. [27] Using the TTM was found to be effective in changing the unhealthy diet behaviours of patients with diabetes to healthier ones, resulting in better clinical outcomes and a reduction in HbA1c. [19,22] In addition, the TTM was proven to be effective in changing the exercise behaviour of patients.…”

Section: Discussionmentioning

confidence: 99%

Using the transtheoretical model to enhance self-management activities in patients with type 2 diabetes: a systematic review

Arafat

Ibrahim

Awaisu

2016

J Pharm Health Serv Res

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Objective The objective of this article is to present a review of the literature focusing on the use of the TTM in improving self-management activities in patients with type 2 diabetes. Self-management activities include following a healthier diet, exercising more regularly, enhanced medication adherence and targeting outcomes such as reduction in glycosylated haemoglobin (HbA1c). Methods PubMed, Medline, ScienceDirect and Cochrane databases were searched using predefined terms related to TTM interventions for patients with type 2 diabetes. All study designs were included. The methods used for this review followed the PRISMA statement (Preferred Reporting Items for Systematic Reviews and Meta-analysis). The systematic search was conducted between February and May 2015. Two reviewers independently assessed the relevance of the identified abstracts, extracted data and undertook quality analysis. Key findings Ten studies met the criteria for inclusion in the review. All studies demonstrated some positive self-management outcomes resulting from implementing the TTM intervention. In six studies, the patients reached the action or maintenance stage in the TTM cycle after the TTM intervention. Moreover, the TTM was able to help patients follow a healthier diet (n = 5) and exercise more (n = 3), and it resulted in a reduction in HbA1c (n = 4). The impact of TTM on medication adherence was not apparent. Conclusions The findings from this systematic review provide evidence that TTM interventions are effective in promoting exercise, encouraging participants to pursue a healthier diet and lowering HbA1c levels, but the effect on medication adherence has not been widely studied among patients with type 2 diabetes.

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Section: Discussionmentioning

confidence: 99%

Using the transtheoretical model to enhance self-management activities in patients with type 2 diabetes: a systematic review

Arafat

Ibrahim

Awaisu

2016

J Pharm Health Serv Res

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“…These outcomes pose a threat to health, especially among adults with heart disease and/or diabetes mellitus (Al Hamid et al, 2014). Thus, the investigation and identification of DNOs may improve patient care regarding treatment.…”

Section: Discussionmentioning

confidence: 99%

Unsatisfactory glycemic control in type 2 Diabetes mellitus patients: predictive factors and negative clinical outcomes with the use of antidiabetic drugs

Marczynski

Cortellazzi

Barberato‐Filho

et al. 2016

Braz. J. Pharm. Sci.

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Many factors can interfere with glycemic control in patients with type 2 diabetes mellitus and this patient group has an increased risk of experiencing drug-related negative outcomes (DNO). The aim of this study was to identify the predictive factors of unsatisfactory glycemic control and DNO in this group of patients. A cross-sectional study was conducted collecting data from prescriptions and interviews with 100 patients of the Endocrinology Clinic of the Hospital Complex of Sorocaba, São Paulo, Brazil. Variables associated with unsatisfactory glycemic control were determined and the DNO associated with antidiabetic drugs identified. Age (<65 years) (OR=4.09), family history of diabetes (OR=3.24), use of combined therapy to treat diabetes (2-4 antidiabetic drugs) (OR=5.13) and presence of DNO (OR=5.92) were found to be predictive factors for poor patient glycemic control. DNO were observed in 49% of the patients and were caused predominantly by ineffectiveness in patients with poor glycemic control (p<0.05). There was no significant difference between groups (satisfactory and unsatisfactory glycemic control) for DNO caused by safety issues (p>0.05). Characterization of the profile of patients with uncontrolled diabetes and of aspects associated with drug treatment can contribute to the planning of interventions to improve patient care.Uniterms: Type 2 Diabetes mellitus. Type 2 Diabetes mellitus/study/drugs use. Pharmaceutical care. Drug-related negative outcomes.

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“…Factors that contribute to medical errors in prescription or dispensing are also at the root of the PEs made by patients themselves with medicines at home [3,48,[86][87][88]: the pre-schooler or elderly population, dependence on a caregiver, comorbidity, complexity of therapeutic regimen, being chronically ill, low health literacy or barriers in communication with caregivers, certain beliefs, and socioeconomic and lifestyle related factors can also contribute to MEs [89]. Among pre-schoolers, PEs are due above all to difficulties in administering the correct dose and excessive use of anti-pyretic drugs.…”

Section: Discussionmentioning

confidence: 99%

A systematic review of patient medication error on self-administering medication at home

Mira

Lorenzo

Guilabert

et al. 2015

Expert Opinion on Drug Safety

101

100

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The frequency of PE was situated between 19 and 59%. The elderly and the preschooler population constituted a higher number of mistakes than others. The most common were: incorrect dosage, forgetting, mixing up medications, failing to recall indications and taking out-of-date or inappropriately stored drugs. The majority of these mistakes have no negative consequences. Health literacy, information and communication and complexity of use of dispensing devices were identified as causes of PEs. Apps and other new technologies offer several opportunities for improving drug safety.

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A systematic review of qualitative research on the contributory factors leading to medicine-related problems from the perspectives of adult patients with cardiovascular diseases and diabetes mellitus

Cited by 31 publications

References 33 publications

Using the transtheoretical model to enhance self-management activities in patients with type 2 diabetes: a systematic review

Using the transtheoretical model to enhance self-management activities in patients with type 2 diabetes: a systematic review

Unsatisfactory glycemic control in type 2 Diabetes mellitus patients: predictive factors and negative clinical outcomes with the use of antidiabetic drugs

A systematic review of patient medication error on self-administering medication at home

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