A systematic review of primary ileostomy site malignancies

Morada, Anthony; Senapathi, Sri Harshavardhan; Bashiri, Amir; Chai, Seungwoo; Cagir, Burt

doi:10.1007/s00464-021-08847-7

Cited by 3 publications

(7 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For unexplained reasons, a median duration of 1 year lapsed between the stoma biopsy and resection. 52 In this same report, 6% ( n = 4 patients) developed a recurrence of cancer during the median follow-up of 0.75 years. 52…”

Section: Cancer At Stoma Sitementioning

confidence: 82%

“…52 In this same report, 6% ( n = 4 patients) developed a recurrence of cancer during the median follow-up of 0.75 years. 52…”

Section: Cancer At Stoma Sitementioning

confidence: 82%

“…For unexplained reasons, a median duration of 1 year lapsed between the stoma biopsy and resection. 52 In this same report, 6% (n ¼ 4 patients) developed a recurrence of cancer during the median follow-up of 0.75 years. 52 Hypotheses for the etiology of these cancers include the presence of chronic irritation at the mucocutaneous junction, migration of colorectal mucosa into the ileostomy, and colonic metaplasia within ileostomy mucosa.…”

Section: Cancer At Stoma Sitementioning

confidence: 82%

“…53 A recent systematic review by Morada et al found a total of 91 patients in the world literature with cancer at an ileostomy site; 67% of the stomas were created in IBD patients and 19% for familial adenomatous polyposis. 52 The mean time from stoma formation to development of cancer was 29 years for the whole group and 31 years in IBD patients. No gender-specific prevalence was seen.…”

Section: Cancer At Stoma Sitementioning

confidence: 96%

“…Ileostomies are associated with multiple chronic complications and skin conditions such as skin irritation, bleeding, and appliance fit challenges. 52 A very rare complication is development of carcinoma at the stoma site. The first case of cancer at an ileostomy site was reported by Sigler and Jedd in 1969.…”

Section: Cancer At Stoma Sitementioning

confidence: 99%

See 4 more Smart Citations

Small Bowel Carcinoma in the Setting of Inflammatory Bowel Disease

Bhatt

Mathis

2023

Clin Colon Rectal Surg

View full text Add to dashboard Cite

Small bowel carcinomas are rare in the general population, but the incidence is increasing. Patients with inflammatory bowel diseases (IBDs) are at significantly higher risk of small bowel adenocarcinomas than their non-IBD counterparts, with Crohn's patients having at least a 12-fold increased risk and ulcerative colitis patients with a more controversial and modest 2-fold increased risk compared with the general population. IBD patients with small bowel carcinomas present with nonspecific symptoms that overlap with typical IBD symptoms, and this results in difficulty making a preoperative diagnosis. Cross-sectional imaging is rarely diagnostic, and most cancers are found incidentally at the time of surgery performed for an IBD indication. As such, most small bowel carcinomas are found at advanced stages and carry a poor prognosis. Oncologic surgical resection is the treatment of choice for patients with locoregional disease with little evidence available to guide adjuvant therapy. Patients with metastatic disease are treated with systemic chemotherapy, and surgery is reserved for palliation in this population. Prognosis is poor with few long-term survivors reported.

show abstract

Section: Cancer At Stoma Sitementioning

confidence: 82%

“…52 In this same report, 6% ( n = 4 patients) developed a recurrence of cancer during the median follow-up of 0.75 years. 52…”

Section: Cancer At Stoma Sitementioning

confidence: 82%

Section: Cancer At Stoma Sitementioning

confidence: 82%

Section: Cancer At Stoma Sitementioning

confidence: 96%

Section: Cancer At Stoma Sitementioning

confidence: 99%

See 3 more Smart Citations

Small Bowel Carcinoma in the Setting of Inflammatory Bowel Disease

Bhatt

Mathis

2023

Clin Colon Rectal Surg

View full text Add to dashboard Cite

show abstract

Tumour Recurrence in peristomal skin: a case report

Wai,

Chan,

Lam

et al. 2023

Gastrointestinal Nursing

View full text Add to dashboard Cite

Peristomal skin recurrences of colorectal cancer after excision of the primary are rare. Clinically, it presents as a subcutaneous mass throughout the abdominal wall and progressively extends on the abdomen as a skin granuloma. Two colorectal cancer patients (an 83-year-old man, previously treated with left hemicolectomy and right exteriorisation for an obstructive tumour of the descending colon, Stage IV mucinous, poorly differentiated adenocarcinoma, and a 60-year-old man who finished the Hartmann's operation and small bowel resection for a perforated and locally advanced cancer of the descending colon) presented tumour recurrences in their peristomal skin. In both patients, the initial presentation was a tiny mucocutaneous skin granuloma. Subsequently, it became a large-sized, atypical, fungated tumour growth, which was complicated with persistent bleeding. A skin biopsy demonstrated an infiltration of adenocarcinoma throughout the dermis and was diagnosed as a local recurrence accompanied by peristomal skin metastasis. Although abdominal skin metastasis of colorectal cancer is rare, it is often a sign of intraabdominal recurrence. Therefore, any unusual skin lesions around the incision scar or stoma should be early biopsied to rule out local metastasis. Stoma nurse specialists play a crucial role in conducting stoma examinations, which involve both stoma and abdominal assessments. Point of care using ultrasound; clinical photos; telehealth; and patient empowerment could be advanced to facilitate early identification of stomal complications for timely investigation and treatment.

show abstract