A systematic review of antipsychotic agents for primary delusional infestation

McPhie, Meghan L.; Kirchhof, Mark G.

doi:10.1080/09546634.2020.1795061

Cited by 13 publications

(14 citation statements)

References 57 publications

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“…They identify engaging and communicating with a patient who has delusions as a major challenge for clinicians. They describe antipsychotic medication as an effective treatment, which was again confirmed in the most recent systematic review on the subject published in 2020 (McPhie 2020). In their review McPhie and Kirchhof confirm the impressive response rates for first- and second-generation antipsychotics that had been reported previously (Lepping 2007).…”

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confidence: 74%

Cogito, ergo praedico(I think, therefore I predict)

Lepping

2021

BJPsych advances

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confidence: 74%

Cogito, ergo praedico(I think, therefore I predict)

Lepping

2021

BJPsych advances

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“…There are four studies wherein quetiapine has been utilized for treating delusional parasitosis in a total of nine patients with dosages ranging from 25 to 800 mg/day [ 17 ]. An improvement in the patients’ symptoms was reported in all these studies [ 17 ]. In the case reported herein, low-dose quetiapine proved effective in treating this condition.…”

Section: Discussionmentioning

confidence: 99%

A Case of Delusional Parasitosis With Folie à Deux Treated With Low-Dose Quetiapine

Kalovidouri¹,

Kowalewski²,

Mos³

et al. 2022

Cureus

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A patient with a three-month history of persistent delusions of infestation presented to the emergency department with suicidal ideation secondary to complaints of worsening pruritus. Routine investigations failed to disclose any underlying organic cause for her pruritic sensations. The patient ascribed these to a parasitic infestation acquired following a brief stay at her maternal aunt’s residence. Following a thorough psychiatric assessment and collateral history obtained from her aunt, it became clear that both the patient and her aunt held similar delusions of infestation. Her aunt was found to be the main inducer. The patient was admitted, successfully treated with low-dose quetiapine, and eventually deemed fit for discharge. Delusional parasitosis and folie à deux are both rare conditions that may sometimes co-occur.

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“…However, the vast majority of patients currently receive antipsychotic medications (although patients are extremely reluctant to take them because they firmly believe that they suffer from an infestation and that it is not “in their mind”) [ 55 ]. More recently, McPhie and Kirchhof [ 56 ] carried out a systematic review of studies examining the effectiveness of typical and atypical antipsychotic medications for primary delusional infestation (both generations of antipsychotics, typical (pimozide was the most commonly reported) and atypical (risperidone was the most common) had favorable outcomes, but the conclusion of this review was that there was a lack of data to strongly support the clinical utility of antipsychotic treatment. The problem could well be one of adherence.…”

Section: Collaboration With Dermatologistsmentioning

confidence: 99%

Collaboration between Psychiatrists and Other Allied Medical Specialists for the Treatment of Delusional Disorders

et al. 2022

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Background: There is increasing evidence that individuals with psychosis are at increased risk for cardiovascular disease, diabetes, metabolic syndrome, and several other medical comorbidities. In delusional disorder (DD), this is particularly so because of the relatively late onset age. Aims: The aim of this narrative review is to synthesize the literature on the necessity for medical collaboration between psychiatrists and other specialists. Methods: A non-systematic narrative review was carried out of papers addressing referrals and cooperation among specialists in the care of DD patients. Results: Psychiatrists, the primary care providers for DD patients, depend on neurology to assess cognitive defects and rule out organic sources of delusions. Neurologists rely on psychiatry to help with patient adherence to treatment and the management of psychotropic drug side effects. Psychiatrists require ophthalmology/otolaryngology to treat sensory deficits that often precede delusions; reciprocally, psychiatric consults can help in instances of functional sensory impairment. Close collaboration with dermatologists is essential for treating delusional parasitosis and dysmorphophobia to ensure timely referrals to psychiatry. Conclusions: This review offers many other examples from the literature of the extent of overlap among medical specialties in the evaluation and effective treatment of DD. Optimal patient care requires close collaboration among specialties.

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A systematic review of antipsychotic agents for primary delusional infestation

Cited by 13 publications

References 57 publications

Cogito, ergo praedico(I think, therefore I predict)

Cogito, ergo praedico(I think, therefore I predict)

A Case of Delusional Parasitosis With Folie à Deux Treated With Low-Dose Quetiapine

Collaboration between Psychiatrists and Other Allied Medical Specialists for the Treatment of Delusional Disorders

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