A Systematic Review of Anti-malarial Properties, Immunosuppressive Properties, Anti-inflammatory Properties, and Anti-cancer Properties of Artemisia Annua

Abstract

Artemisia annua belongs to the asteraceae family, indigenous to the mild climate of Asia. The aim of this study was to overview its anti-malarial properties, immunosuppressive properties, anti-inflammatory properties and anti-cancer properties. This systematic review was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. The initial search strategy identified approximately ninety eight references. In this study, forty six studies were accepted for further screening and met all of our inclusion. The search terms were “Artemisia annua”, “therapeutic properties”, “and pharmacological effects”. Artemisia annua is commonly used for its anti-malarial, immunosuppressive anti-inflammatory properties. Artemisia annua contributes to the treatment of various diseases such as diabetes, heart diseases, arthritis and eczema and possesses various effects such as antibacterial, antioxidant, anticoccidial, and antiviral effects. Furthermore, it was said to be good for cancer treatment. In this study, anti-malarial, immunosuppressive, anti-inflammatory properties of this plant are presented using published articles in scientific sites.

Plants-Derived Biomolecules as Potent Antiviral Phytomedicines: New Insights on Ethnobotanical Evidences against Coronaviruses

“…This Chinese medicinal plant has been used for a long time to treat various diseases such as bronchitis and hemorrhoids, and is potentially effective for its anti-malarial, antiviral, anticancer, etc., properties [ 45 , 46 , 47 ]. However, Artemisia annua ( A. annua ) has been known to possess antiviral activity and currently is in use for the treatment of Poliovirus, HIV, RSV, HSV1, hepatitis C, type 2 dengue virus and human cytomegalovirus [ 29 , 48 ].…”

Effects of herbal multicomponent dietary supplement in experimental pneumonia

“…In addition antiinflammatory properties of Tanacetum vulgare [27], Inula helenium L [28], Melissa officinalis [17], Artemisia vulgaris L [29] can all increase oxidative stress and induce mitochondrial-related apoptosis. These compounds have been traditionally used in anti-cancer therapy.…”

Artemisia afra and hypertension

“…In South Africa Artemisia afra is a well-known herbal medicine used for various inflammatory conditions. [20][21][22][23] Hypertensives have higher interleukin-6 as per a study from Boston as shown by this graph…”