A systematic review including an additional pediatric case report: Pediatric cases of mammary analogue secretory carcinoma

Ngouajio, Amanda L.; Drejet, Sarah M.; Phillips, Drew; Summerlin, Don‐John; Dahl, John P.

doi:10.1016/j.ijporl.2017.07.004

Cited by 28 publications

(21 citation statements)

References 29 publications

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“…Our cohort had two pediatric SC cases (14 and 15 years old). To our knowledge, 16 cases of pediatric SC have been reported in the literature, and SC should be included in differential diagnosis of pediatric salivary gland tumors.…”

Section: Discussionmentioning

confidence: 99%

Hemorrhage of MRI and Immunohistochemical Panels Distinguish Secretory Carcinoma From Acinic Cell Carcinoma

Kuwabara

Yamamoto

Takato

et al. 2018

Laryngoscope Investig Oto

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ObjectivesSecretory carcinoma (SC, mammary analogue secretory carcinoma) is a salivary gland tumor with ETV6‐NTRK3 gene fusion, and its differential diagnosis includes acinic cell carcinoma (ACC). As hemorrhage is often seen in SC, we hypothesized that magnetic resonance imaging (MRI) and immunohistochemical analyses could distinguish SC from ACC.Study DesignRetrospective study.MethodsWe used ETV6‐NTRK3 gene fusion analyses to reclassify 19 parotid gland tumors that had previously been diagnosed as SC or ACC, and then investigated hemorrhage in both hematoxylin‐eosin (H&E)‐stained sections and MRIs, and immunohistochemical expression of S‐100, mammaglobin, DOG1, and α‐amylase.ResultsThe 19 tumors were genetically reclassified into 11 (58%) SC and 8 (42%) ACC. Combined S‐100 and mammaglobin were specific for SC; whereas DOG1 was specific for ACC, and α‐amylase was expressed only in 4 ACC cases (50%). H&E staining showed hemorrhage with hemosiderin deposition in all SC cases, and T2‐weighted MRI showed hypointense areas in all investigated SC cases, but not in ACC.ConclusionHemorrhage with hemosiderin deposition is frequently present in SC, and hemorrhage findings in MRI and an immunohistochemical panels for S‐100, mammaglobin and DOG1 can distinguish SC from ACC.Level of Evidence3b

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Section: Discussionmentioning

confidence: 99%

Hemorrhage of MRI and Immunohistochemical Panels Distinguish Secretory Carcinoma From Acinic Cell Carcinoma

Kuwabara

Yamamoto

Takato

et al. 2018

Laryngoscope Investig Oto

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“…In addition, we reviewed all published cases of SC in which follow‐up data of 6 months or greater were available by conducting a PubMed search using the terms “mammary analog secretory carcinoma,” “mammary analogue secretory carcinoma,” “secretory carcinoma,” and “MASC.” SC‐like tumors of nonsalivary gland origin were excluded. We identified 26 case reports and series totaling 170 patients with reported outcome data as shown in Table . Patient data from all publications were combined in order to assess recurrence rate and pattern.…”

Section: Methodsmentioning

confidence: 99%

“…We identified 26 case reports and series totaling 170 patients with reported outcome data as shown in Table 1. [1][2][3]6,7,9,10,[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] Patient data from all publications were combined in order to assess recurrence rate and pattern. Patients were not doublecounted if appearing in more than one publication and due to variable follow-up reporting, actuarial survival analysis was not attempted.…”

Section: Methodsmentioning

confidence: 99%

Secretory carcinoma of the major salivary gland: Provincial population‐based analysis of clinical behavior and outcomes

Ayre

Hyrcza

et al. 2018

Head & Neck

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Background Our aim was to identify the number of cases of secretory carcinoma (SC) of the major salivary gland in a population‐based cohort and review its clinical behavior with long‐term follow‐up. Methods All malignant salivary gland tumors (MSGTs) diagnosed between 1980 and 2014 were assessed for histological features compatible with SC and 140 were selected for further analysis. Results Twenty two new cases of SC were identified, 19 of which were originally classified as acinic cell carcinoma, and 3 as adenocarcinoma, not otherwise specified (NOS). Lymph node involvement was less common in SC tumors (5%) than in the control group (11%). Disease recurrence was seen less frequently in SC (9%) than the control group (20%). Mean disease‐free survival was 192 months for SC compared with 162 months for controls (P = 0.15). Conclusion The clinical course of SC is typically indolent with a low risk of relapse not significantly different from other low‐grade MSGT.

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“…1,2 The average age of presentation of the tumor is in the fourth or fifth decade, with only a few cases being reported in children and adolescents, and is slightly more prevalent in men. 2,3,6 Mammary analogue secretory carcinoma commonly presents as a slow growing, painless mass. The size of the mass ranges from 0.2 to 5.5 cm, with an average size of 1.7 cm.…”

Section: Presentationmentioning

confidence: 99%

Atypical Presentation of Mammary Analogue Secretory Carcinoma of the Lip

Yassin‐Kassab

Gainor²,

Sufyan³

2020

Ear Nose Throat J

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Mammary analogue secretory carcinoma (MASC) of the salivary gland is a rare tumor that was first described by Skalova et al in 2010, and since then, only a few hundred cases have been reported in the literature. Prior to Skalova’s report, MASC was histologically misclassified as acinic cell carcinoma (ACC), pleomorphic adenoma, mucoepidermoid carcinoma, or adenocarcinoma, not otherwise specified. Mammary analogue secretory carcinoma has a low incidence rate overall, accounting for less than 0.3% of all salivary gland tumors. Histopathologic and cytogenic analysis of MASC is identical to secretory carcinoma of the breast, leading to the proposed name by Skalova. The purpose of this case presentation is to describe an atypical presentation of MASC, to compare this case with the classic description of MASC, and to contrast the various features of MASC to ACC in order to improve the accuracy of future diagnoses and help guide treatment.

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A systematic review including an additional pediatric case report: Pediatric cases of mammary analogue secretory carcinoma

Cited by 28 publications

References 29 publications

Hemorrhage of MRI and Immunohistochemical Panels Distinguish Secretory Carcinoma From Acinic Cell Carcinoma

Hemorrhage of MRI and Immunohistochemical Panels Distinguish Secretory Carcinoma From Acinic Cell Carcinoma

Secretory carcinoma of the major salivary gland: Provincial population‐based analysis of clinical behavior and outcomes

Atypical Presentation of Mammary Analogue Secretory Carcinoma of the Lip

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