A Systematic Review and Meta-Analysis of Diagnostic Performance of MRI for Evaluation of Acute Appendicitis

Duke, Eugene; Kalb, Bobby; Arif-Tiwari, Hina; Daye, Z. John; Gilbertson-Dahdal, Dorothy; Keim, Samuel M.; Martín, Diego R.

doi:10.2214/ajr.15.14544

Cited by 134 publications

(80 citation statements)

References 56 publications

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“…It has been proposed to be used in pregnant patients with abdominal pain when US is inconclusive [33]. Recently, a systematic review and meta-analysis of diagnostic performance of MRI for evaluation of acute appendicitis was published [34]. A total of 30 studies that comprised 2665 patients were reviewed.…”

Section: What Are the Optimal Methods In Diagnosing Iai That Balancesmentioning

confidence: 99%

Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference

et al. 2017

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This paper reports on the consensus conference on the management of intra-abdominal infections (IAIs) which was held on July 23, 2016, in Dublin, Ireland, as a part of the annual World Society of Emergency Surgery (WSES) meeting. This document covers all aspects of the management of IAIs. The Grading of Recommendations Assessment, Development and Evaluation recommendation is used, and this document represents the executive summary of the consensus conference findings.

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Section: What Are the Optimal Methods In Diagnosing Iai That Balancesmentioning

confidence: 99%

Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference

et al. 2017

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“…Three previously published systematic reviews and meta‐analyses have investigated the diagnostic performance of MRI for acute appendicitis in children . Nonetheless, we performed this current meta‐analysis for the following reasons.…”

Section: Discussionmentioning

confidence: 99%

“…Its high soft‐tissue contrast resolution, lack of ionizing radiation, and reduced operator dependency are strong advantages in children. Despite a substantial number of studies on the use of MRI in the evaluation of acute appendicitis in children and adolescents, there are only a few published systematic reviews and meta‐analyses . Hence, we conducted a systematic review and meta‐analysis with a larger number of included studies and using hierarchical models to evaluate the diagnostic performance of MRI and the negative appendectomy rate for suspected appendicitis in pediatric patients.…”

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confidence: 99%

Performance of MRI for suspected appendicitis in pediatric patients and negative appendectomy rate: A systematic review and meta‐analysis

Kim

Suh

Yoon

et al. 2017

Magnetic Resonance Imaging

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“…However, due to the potential risk of malignancy [15, 30], serial US [31] and magnetic resonance imaging (MRI) [32, 33] have recently been suggested as alternatives to CT. A meta-analysis proposed MRI as an optional first line imaging modality for suspected appendicitis in children [32]. However, availability, cost, and the possible need for sedation in young children make the practical use of MRI called into question.…”

Section: Discussionmentioning

confidence: 99%

Ultrasound for Appendicitis: Performance and Integration with Clinical Parameters

Löfvenberg

Salö

2016

BioMed Research International

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Objective. To evaluate the performance of ultrasound in pediatric appendicitis and the integration of US with the pediatric appendicitis score (PAS) and C-reactive protein (CRP). Method. An institution-based, retrospective study of children who underwent abdominal US for suspected appendicitis between 2012 and 2015 at a tertiary pediatric surgery center. US results were dichotomized, with a nonvisualized appendix considered as a negative examination. Results. In total, 438 children were included (mean 8.5 years, 54% boys), with an appendicitis rate of 29%. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for US were 82%, 97%, 92%, and 93%, respectively, without significant age or gender differences. Pediatric radiologists had significantly higher sensitivity compared to general radiologists, 88% and 71%, respectively (p < 0.01), but no differences were seen for specificity, PPV, and NPV. The sensitivity, NPV, and negative likelihood ratio for the combination of negative US, PAS < 5, and CRP < 5 mg/L were 98%, 98%, and 0.05 (95% CI 0.03–0.15). Conclusion. US may be a useful tool for evaluating children with suspected appendicitis, regardless of age or gender, and should be the first choice of imaging modalities. Combining US with PAS and CRP may reduce several unnecessary admissions for in-hospital observation.

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A Systematic Review and Meta-Analysis of Diagnostic Performance of MRI for Evaluation of Acute Appendicitis

Abstract: MRI has a high accuracy for the diagnosis of acute appendicitis, for a wide range of patients, and may be acceptable for use as a first-line diagnostic test.

Cited by 134 publications

References 56 publications

Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference

Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference

Performance of MRI for suspected appendicitis in pediatric patients and negative appendectomy rate: A systematic review and meta‐analysis

Ultrasound for Appendicitis: Performance and Integration with Clinical Parameters

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