A systematic review and meta-analysis of sex differences in cannabis use disorder amongst people with comorbid mental illness

Kozak, Karolina; Smith, Philip H.; Lowe, Darby; Weinberger, Andrea H.; Cooper, Ziva D.; Rabin, Rachel A.; George, Tony P.

doi:10.1080/00952990.2021.1946071

Cited by 16 publications

(11 citation statements)

References 100 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 63 Kozak et al found that the association between anxiety disorders and cannabis use might indicate that mental illness inclusive of ADHD can contribute to the increased likelihood of cannabis use – indicating that to cope with stressors and anxiety, females are more vulnerable to self-medicate with cannabis and are susceptible to developing and maintaining cannabis use. 64 , 65 …”

Section: Discussionmentioning

confidence: 99%

Differences in alcohol and cannabis use amongst substance use disorder patients with and without comorbid attention-deficit/hyperactivity disorder

2022

View full text Add to dashboard Cite

Background: Substance use disorders (SUDs) continue to be a public health problem. Attention-deficit/hyperactivity disorder (ADHD) is seen as a risk factor for SUD. Prevalence of alcohol and cannabis use amongst adults with SUD and comorbid ADHD impacts both disorders cognitively and behaviourally.Aim: Our study aimed to compare alcohol and cannabis use between treatment-seeking SUD patients with ADHD and SUD patients without ADHD symptomatology.Setting: Various rehabilitation centres, including the South African National Council on Alcoholism and Drug Dependence (SANCA) Centres, and Private and Provincial Government Substance Abuse Treatment Centres.Methods: A cross-sectional study of adults on drug rehabilitation was conducted. Data on socio-demographic information and alcohol and cannabis use from 185 post-detox inpatients were collected. Diagnoses were based on DSM-IV criteria. Attention-deficit/hyperactivity disorder diagnosis was confirmed by the Diagnostic-Interview for ADHD in Adults (DIVA 2.0). SUD+ADHD (n = 52) and SUD-ADHD (n = 128) groups were compared on alcohol and cannabis use as a function of gender.Results: No significant differences in the use of alcohol between the SUD+ADHD and SUD-ADHD groups were found. However, the SUD+ADHD group showed increased cannabis consumption. Especially, the SUD+ADHD females showed an earlier age of onset of cannabis use than the SUD-ADHD females and revealed that they use cannabis for a longer period compared with the SUD-ADHD females and SUD+ADHD and SUD-ADHD males.Conclusion: The results revealed the relationship between ADHD and cannabis use, especially amongst females with ADHD and reinforce the need to consider ADHD in cannabis use SUD in clinical interventions.

show abstract

Section: Discussionmentioning

confidence: 99%

Differences in alcohol and cannabis use amongst substance use disorder patients with and without comorbid attention-deficit/hyperactivity disorder

2022

View full text Add to dashboard Cite

show abstract

“…For example, men have an earlier age of onset and a higher probability of cannabis use [ 22 ]. Men also have a two-fold risk of continuing cannabis use when compared to women and higher risk rates of developing CUD [ 22 , 23 ]. However, the general finding that men are overrepresented in addiction treatment settings could be biased due to specific facilitators and barriers to women seeking addiction treatment, as has been shown in clinical investigations [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

A Nationwide Study of Inpatient Case Rate Incidence of Cannabis-Related Diagnoses in Switzerland

Pfeifer

Auer

Baggio

et al. 2022

Int J Public Health

View full text Add to dashboard Cite

Objectives: Cannabis is the most commonly used illicit substance and has been associated with mental health issues. In this study, we examined trends in hospitalizations due to cannabis use.Methods: Data were obtained from the Swiss Federal Statistics Office and comprised hospital main diagnoses, gender, age group and region of all psychiatric inpatient cases in Switzerland from 1998 to 2020. We performed trend analyses of annual case rates with cannabinoid-related diagnoses and compared them to trend analyses of alcohol-related and psychotic disorders.Results: Case rates of CRDs significantly increased in the observed time period. From all psychiatric main diagnoses, CRDs were overrepresented in the age groups of 15–24 and 25–44 years.Conclusion: We found a sharp increase in hospitalizations for CRD. Future studies should test whether changes in the upcoming cannabis regulation, which can facilitate the implementation of interventions to address mental health among users, impact future hospitalization rates of CRD.

show abstract

Section: Methodsmentioning

confidence: 99%

“…Only men 45 and predominantly men 36 were recruited for the included schizophrenia studies. The gender distribution of these samples reflects that rates of CUD are elevated among men with schizophrenia compared to women with schizophrenia, 47 and that women with schizophrenia are more likely to be polydrug users rather than using solely cannabis. 48 All participants met criteria for either current cannabis dependence or CUD as assessed by the Structural Clinical Interview for DSM-IV or DSM-5, respectively (hereon in both cannabis dependence and CUD will be collectively referred to as CUD).…”

Section: Participantsmentioning

confidence: 99%

Does tobacco dependence worsen cannabis withdrawal in people with and without schizophrenia‐spectrum disorders?

et al. 2023

Self Cite

View full text Add to dashboard Cite

Background and Objectives: Rates of cannabis use disorder (CUD) are higher in people with schizophrenia than in the general population. Irrespective of psychiatric diagnosis, tobacco co-use is prevalent in those with CUD and leads to poor cannabis cessation outcomes. The cannabis withdrawal syndrome is well-established and increases cannabis relapse risk. We investigated whether cannabis withdrawal severity differed as a function of high versus no/low tobacco dependence and psychiatric diagnosis in individuals with CUD. Method: Men with CUD (N = 55) were parsed into four groups according to schizophrenia diagnosis and tobacco dependence severity using the Fagerstrom Test for Nicotine Dependence (FTND): men with schizophrenia with high tobacco dependence (SCT+, n = 13; FTND ≥ 5) and no/low tobacco dependence (SCT−, n = 22; FTND ≤ 4), and nonpsychiatric controls with high (CCT+, n = 7; FTND ≥ 5) and no/low (CCT−, n = 13; FTND ≤ 4) tobacco dependence. Participants completed the Marijuana Withdrawal Checklist following 12-h of cannabis abstinence.Results: There was a significant main effect of tobacco dependence on cannabis withdrawal severity (p < .001). Individuals with high tobacco dependence had significantly greater cannabis withdrawal severity (M = 13.85 [6.8]) compared to individuals with no/low tobacco dependence (M = 6.49, [4.9]). Psychiatric diagnosis and the interaction effects were not significant. Lastly, cannabis withdrawal severity positively correlated with FTND (r = .41, p = .002). Conclusion and ScientificSignificance: Among individuals with CUD and high tobacco dependence, cannabis withdrawal severity was elevated twofold, irrespective of diagnosis, relative to individuals with CUD and no/low tobacco dependence.Findings from this study emphasize the importance of addressing tobacco co-use when treating CUD.

show abstract

A systematic review and meta-analysis of sex differences in cannabis use disorder amongst people with comorbid mental illness

Cited by 16 publications

References 100 publications

Differences in alcohol and cannabis use amongst substance use disorder patients with and without comorbid attention-deficit/hyperactivity disorder

Differences in alcohol and cannabis use amongst substance use disorder patients with and without comorbid attention-deficit/hyperactivity disorder

A Nationwide Study of Inpatient Case Rate Incidence of Cannabis-Related Diagnoses in Switzerland

Does tobacco dependence worsen cannabis withdrawal in people with and without schizophrenia‐spectrum disorders?

Contact Info

Product

Resources

About