Abstract:Alcohol Use Disorder (AUD) is a complex mental disease with a large treatment need. However, the clinically available therapeutic approaches are limited and thus new treatment targets are warranted. One approach to discover new treatment targets is transcriptomic profiling of key brain regions of the addiction neurocircuitry in animal models of AUD and/or in post-mortem brain tissue from deceased AUD patients. Unfortunately, those studies suffer from large heterogeneity and low sample sizes. Here we used a cro… Show more
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