A systematic review and meta-analysis of proteomic and metabolomic alterations in anaphylaxis reactions
Adrienne Astrid Gallizzi,
Almut Heinken,
Rosa-Maria Guéant-Rodriguez
et al.
Abstract:BackgroundAnaphylaxis manifests as a severe immediate-type hypersensitivity reaction initiated through the immunological activation of target B-cells by allergens, leading to the release of mediators. However, the well-known underlying pathological mechanisms do not fully explain the whole variety of clinical and immunological presentations. We performed a systemic review of proteomic and metabolomic studies and analyzed the extracted data to improve our understanding and identify potential new biomarkers of a… Show more
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