A systematic review and meta‐analysis of the effects of fluoride toothpastes on the prevention of dental caries in the primary dentition of preschool children

Santos, Ana Paula Pires dos; Nadanovsky, Paulo; Oliveira, Branca Heloísa de

doi:10.1111/j.1600-0528.2012.00708.x

Cited by 147 publications

(152 citation statements)

References 42 publications

(69 reference statements)

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“…Th e total score ranged from 0 to 100 for the CPQ [8][9][10] and from 0 and 148 for the CPQ [11][12][13][14] . Higher scores denote a greater impact of oral health on quality of life.…”

Section: Methodsmentioning

confidence: 99%

“…OHRQOL was assessed using the Brazilian versions of the Child Perception Questionnaire (CPQ [8][9][10] ), which was validated by Barbosa et al 9 , and the adolescent CPQ (CPQ [11][12][13][14], which was validated by Gourgand et al 10 Th ese instruments were used to assess the impact of oral health on the quality of life of four groups of subjects: 8-10-year-old children with and without fl uorosis, and 11-12-year-old adolescents with and without fl uorosis.…”

Section: Methodsmentioning

confidence: 99%

“…The indices of fluorosis were dichotomized as either the presence of fluorosis (TFI scores 1-9) or no fluorosis (TFI score 0) and associated with sociodemographic variables by performing the chi-square test and Fisher's exact test. The overall mean and domain scores of the CPQ [8][9][10] and CPQ [11][12][13][14] were compared between the groups with and without fluorosis using the Mann-Whitney test.…”

Section: Methodsmentioning

confidence: 99%

“…Fluoride toothpastes have been associated with an increase in fl uorosis 3 , but a systematic review showed that the evidence for this association is weak and unreliable 7 . Moreover, a meta-analysis demonstrated that conventional fl uoride dentifrices are eff ective in reducing dental caries in the primary dentition and should be recommended for preschool children 8 . Th us, it is important to evaluate the impact that dental fl uorosis has on quality of life.…”

Section: Introductionmentioning

confidence: 99%

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Impact of dental fluorosis on the quality of life of children and adolescents

Lima

Neta

Moura

et al. 2014

Rev. odontol. UNESP

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ResumoIntrodução: A fluorose dentária é um distúrbio de alta prevalência decorrente da ingestão de íons fluoretos. Medidas preventivas para evitá-la ainda são controversas. Assim, conhecer o impacto que a fluorose pode causar na qualidade de vida de indivíduos é importante para o planejamento de políticas públicas de saúde. Objetivo: Avaliar o impacto da fluorose dentária sobre a qualidade de vida relacionada à saúde bucal (QVRSB) de crianças e adolescentes. Material e método: Foram avaliados 300 indivíduos na faixa etária de 8 a12 anos. O diagnóstico de fluorose foi realizado segundo o índice Thylstrup e Fejerskov e a qualidade de vida foi avaliada utilizando os questionários de Percepção da Criança 8-10 e 11-14. Foram incluídos pacientes com oito incisivos permanentes com coroas totalmente irrompidase excluídos os que apresentavam restaurações extensas, dentes fraturados, outros defeitos do esmalte dentário e os que usavam aparelho ortodôntico fixo. Os dados foram analisados no programa SPSS  (versão 18; Chicago, IL) e realizaram-se os teste Qui-quadrado, Fisher e Mann-Whitney. Foram considerados significantes valores de p<0,05. Resultado: A prevalência de fluorose foi 64,7%, sendo os graus leve e muito leve responsáveis por 80,3% dos casos. Crianças e adolescentes não tiveram impacto na QVRSB no escore geral e domínios sintomas orais, bem-estar emocional e social (p>0,05). Entretanto, apresentaram impacto no domínio limitação funcional (p = 0,039 e 0,013) para crianças e adolescentes respectivamente). Conclusão: Foi observada associação entre fluorose e qualidade de vida apenas no domínio funcional.Descritores: Fluorose dentária; qualidade de vida; percepção. AbstractIntroduction: Dental fluorosis is a disturbance of high prevalence caused by the ingestion of fluoride ions present mainly in toothpaste. Preventive measures to avoid it are still controversial. Thus, knowing the impact that fluorosis can cause on the population's quality of life it is important for planning public health policies. Objective: To evaluate the impact of dental fluorosis on the quality of life of children and adolescents. Material and method: We studied 300 subjects aged 8 to 12 years divided into 4 groups: children (8-10 years) and adolescents (10 to 12 years) with and without fluorosis. The diagnosis of fluorosis was performed according to the index Thylstrup and Fejerskov and quality of life was evaluated using Child Perceptions Questionnaire 8-10 and 11-14. The socio-demographic characteristics of the patients were also evaluated. For inclusion in the sample, selected patients should present eight permanent incisors with crowns fully erupted. Patients who had extensive restorations, fractured teeth, other dental enamel defects and who wore braces were excluded. Result: Fluorosis was present in 64.7% of the patients analyzed and in most cases (80.3%) was mild or very mild. In children, the average overall score of the questionnaire was 15.9 for the group without fluorosis and 18.3 for the group with fluorosis (p = 0.255). The te...

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“…Th e total score ranged from 0 to 100 for the CPQ [8][9][10] and from 0 and 148 for the CPQ [11][12][13][14] . Higher scores denote a greater impact of oral health on quality of life.…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Impact of dental fluorosis on the quality of life of children and adolescents

Lima

Neta

Moura

et al. 2014

Rev. odontol. UNESP

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“…Considering that it is based on evidence that sugar exposure is the cause of caries (3) and that the fluoride effect on enamel caries is concentration-dependent (12,13), it is plausible to hypothesize that an increase in the concentration of fluoride could compensate for caries increment caused by increasing sugar exposure. To test this hypothesis the effect of fluoride concentration in toothpaste on the reduction of enamel demineralization, using a pH-cycling model and simulating conditions of higher cariogenic challenge (sugar exposure of 8x and 16x/day), was evaluated.…”

Section: Introductionmentioning

confidence: 99%

Effect of Fluoride Concentration on Reduction of Enamel Demineralization According to the Cariogenic Challenge

et al. 2016

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Fluoride present in toothpaste at 1,100 µg/g is considered effective on caries control. However, under high cariogenic challenge due to increasing sugar exposure, higher fluoride concentration (5,000 µg/g) could be necessary to compensate the unbalance on caries process. This was tested in a pH-cycling regimen, which evaluated the effect of fluoride concentration relative to toothpaste on reduction of enamel demineralization under conditions of two levels of cariogenic challenge. Enamel slabs (n=20) were subjected to two pH-cycling regimens, simulating 8x and 16x/day sugar exposure and were treated with solutions containing: 0 (no fluoride), 275 or 1,250 µg F/mL, resulting in 6 treatment groups: 4-h/0-F; 8-h/0-F; 4-h/275-F; 8-h/275-F; 4-h/1,250-F and 8-h/1,250-F. The 275 and 1,250 µg F/mL concentrations simulate mouth salivary dilution when 1,100 and 5,000 µg/g toothpastes are used. Enamel demineralization was assessed by surface (%SHL) and cross-sectional hardness. Fluoride taken up by enamel was also evaluated. Data were analyzed by ANOVA one-way and Tukey's test. The treatment with 1,250 µg F/mL significantly reduced %SHL compared with 275 µg F/mL (p<0.05), irrespective the level of cariogenic challenge (4-h/1,250-F vs. 4-h/275-F and 8-h/1,250-F vs 8-h/275-F comparisons, respectively). These data were supported by fluoride concentration found in enamel. These findings suggest that higher fluoride concentrations could partly compensate the greater caries risk under higher cariogenic challenge due to increasing sugar exposure.

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Mothers’ Sources of Child Fluoride Information and Misinformation From Social Connections

Burgette

Dahl

et al. 2022

JAMA Netw Open

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Key Points Question From which social relationships do mothers obtain child fluoride information and misinformation? Findings In this qualitative study of 126 mothers of children aged 3 to 5 years, fluoride information and misinformation relating to children were obtained from family members, health care clinicians, and community members. The receipt of inconsistent child fluoride information from multiple sources resulted in confusion and difficulty assessing the accuracy of the fluoride information. Meaning These findings suggest that social relationships can be a potential target for interventions to provide accurate fluoride information related to children.

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A systematic review and meta‐analysis of the effects of fluoride toothpastes on the prevention of dental caries in the primary dentition of preschool children

Abstract: Standard F toothpastes are effective in reducing dental caries in the primary teeth of preschool children and thus their use should be recommended to this age group.

Cited by 147 publications

References 42 publications

Impact of dental fluorosis on the quality of life of children and adolescents

Impact of dental fluorosis on the quality of life of children and adolescents

Effect of Fluoride Concentration on Reduction of Enamel Demineralization According to the Cariogenic Challenge

Mothers’ Sources of Child Fluoride Information and Misinformation From Social Connections

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