A systematic review and meta-analysis of thigmotactic behaviour in the open field test in rodent models associated with persistent pain
Xue Ying Zhang,
Marta Diaz-delCastillo,
Lingsi Kong
et al.
Abstract:Thigmotaxis is an innate predator avoidance behaviour of rodents. To gain insight into how injury and disease models, and analgesic drug treatments affect thigmotaxis, we performed a systematic review and meta-analysis of studies that assessed thigmotaxis in the open field test. Systematic searches were conducted of 3 databases in October 2020, March and August 2022. Study design characteristics and experimental data were extracted and analysed using a random-effects meta-analysis. We also assessed the correla… Show more
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