2011
DOI: 10.1016/j.jvs.2011.02.031
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A systematic review and meta-analysis of the treatments of varicose veins

Abstract: Low-quality evidence supports long-term safety and efficacy of surgery for the treatment of varicose veins. Short-term studies support the efficacy of less invasive treatments, which are associated with less periprocedural disability and pain.

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Cited by 128 publications
(88 citation statements)
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“…The overall results of this research differ from the findings of other published systematic reviews and meta-analyses [84][85][86][87][88][89] in their conclusion that FS, EVLA and RFA offer potentially equally effective alternatives to surgery and, in the case of FS, a cost-effective alternative also. This difference can be explained by the inclusion of more RCT evidence in the present report (approximately three times as many relevant RCTs than any previous review, despite broader criteria in the majority of the previous reviews), the exclusion of non-RCT and noncomparative evidence, and the analysis methods used.…”
Section: Discussioncontrasting
confidence: 99%
“…The overall results of this research differ from the findings of other published systematic reviews and meta-analyses [84][85][86][87][88][89] in their conclusion that FS, EVLA and RFA offer potentially equally effective alternatives to surgery and, in the case of FS, a cost-effective alternative also. This difference can be explained by the inclusion of more RCT evidence in the present report (approximately three times as many relevant RCTs than any previous review, despite broader criteria in the majority of the previous reviews), the exclusion of non-RCT and noncomparative evidence, and the analysis methods used.…”
Section: Discussioncontrasting
confidence: 99%
“…The efficacy of foam sclerotherapy on QOL was recently demonstrated in a single-centre cohort study by Darvall et al These author found that ultrasound-guided foam sclerotherapy for great and small saphenous varicose veins leads to significant improvements in generic and diseasespecific health related QOL for at least 12 months after treatment 12 .…”
Section: Quality Of Lifementioning
confidence: 98%
“…A meta-analysis of these studies shows no significant difference between the two procedures on varicosity recurrence (RR, 0.94; 95% CI, 0.25-3.46; I2 = 50%) [23].…”
Section: Discussionmentioning
confidence: 93%