A System Biology Approach to Explore Host-Pathogen Interaction Under Phytochemical Cross Linkages

Abstract

Phyto-signalling molecules are minute, but tangible that has rigorous roles in any plant-pathogen interaction. Certainly, most of the pathogen alters their biosynthesis, transport, degradation and cellular signalling responses to pave their virulence. Therefore, the gene expressions of such molecules with their correlated defense mechanisms were analysed in Arabidopsis thaliana against Erysiphe orontii (a potential biotroph), Botrytis cinerea (a potential necrotroph), Pseudomonas syringae (a bacterial hemibiotroph), and Phytophthora infestans (a fungal hemibiotroph) using molecular biology/ system biology techniques. The findings strongly suggested that each pathogen has its own unique infection strategy based on up-regulation and down-regulation of host phyto-signalling genes. Our studies also explored four basic pathogenic infection maps based on cross linking phyto-signalling molecules.