A synthetic furanone potentiates the effect of disinfectants on
            <i>Salmonella</i>
            in biofilm

Vestby, Lk K.; Lönn‐Stensrud, Jessica; Møretrø, Trond; Langsrud, Solveig; Aamdal-Scheie, A.; Benneche, T.; Nesse, LL

doi:10.1111/j.1365-2672.2009.04495.x

Cited by 34 publications

(31 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Møretrø and colleagues found that while exposure to acidic peroxygen-based disinfectants (Virkon S) resulted in the 4 log 10 reduction in Salmonella cells, other disinfectants, including hypochlorite and benzalkonium chloride products, did not show sufficient bactericidal effect (49). Vetsby et al also concluded that neither hypochlorite nor benzalkonium chloride achieved a Ͼ4 log 10 reduction, although when combining the disinfectants used with a synthetic furanone, this target was achieved (46). In contrast, Wong et al found that a range of disinfectants, including benzalkonium chloride and sodium hypochlorite, reduced 3-, 5-, and 7-day Salmonella biofilms by Ͼ4 log 10 (27).…”

Section: Discussionmentioning

confidence: 99%

“…This finding may have implications for use of biocides and disinfectants, because studies on efficacy of biocides have generally used only 48-h biofilm (12,46,47,49).…”

Section: Discussionmentioning

confidence: 99%

“…In this paper, we assess biofilm density at 168 h compared with that at 48 h on multiple surfaces and the activity of commonly used chemical disinfectants against early (48-h) and more mature (168-h) Salmonella biofilms for a subset of those strains representing common serovars on a concrete substratum. The chosen concentrations were based on a review of the concentrations used in industry and comparable to those used in other work published in this area (46)(47)(48)(49). These concentrations were also demonstrated to be effective against planktonic cells in preliminary experiments described in this work.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Commonly Used Disinfectants Fail To Eradicate Salmonella enterica Biofilms from Food Contact Surface Materials

Corcoran

Morris

Lappe

et al. 2014

Appl Environ Microbiol

167

View full text Add to dashboard Cite

Salmonellosis is the second most common cause of food-borne illness worldwide. Contamination of surfaces in food processing environments may result in biofilm formation with a risk of food contamination. Effective decontamination of biofilm-contaminated surfaces is challenging. Using the CDC biofilm reactor, the activities of sodium hypochlorite, sodium hydroxide, and benzalkonium chloride were examined against an early (48-h) and relatively mature (168-h) Salmonella biofilm. All 3 agents result in reduction in viable counts of Salmonella; however, only sodium hydroxide resulted in eradication of the early biofilm. None of the agents achieved eradication of mature biofilm, even at the 90-min contact time. Studies of activity of chemical disinfection against biofilm should include assessment of activity against mature biofilm. The difficulty of eradication of established Salmonella biofilm serves to emphasize the priority of preventing access of Salmonella to postcook areas of food production facilities.

show abstract

Section: Discussionmentioning

confidence: 99%

“…This finding may have implications for use of biocides and disinfectants, because studies on efficacy of biocides have generally used only 48-h biofilm (12,46,47,49).…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Commonly Used Disinfectants Fail To Eradicate Salmonella enterica Biofilms from Food Contact Surface Materials

Corcoran

Morris

Lappe

et al. 2014

Appl Environ Microbiol

167

View full text Add to dashboard Cite

show abstract

“…Crop species resistant to one or more species of parasitic plants belonging to the genera Orobanche or Striga were developed. 5 The γ-lactone moiety is found in many natural and synthetic compounds that have diverse biological activities: antibacterial, 6 antitumor, 7 anti-inflammatory agents, 8 analgesics, 9 antimalarial, 10 fungicides, 11 insecticides 12 and herbicides ( Figure 1). 13 The ring of these compounds present diverse patterns of saturation and substitution and most of them have very large carbon skeletons.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and phytotoxicity of 4,5 functionalized tetrahydrofuran-2-ones

Resende¹,

Alvarenga²,

Galindo³

et al. 2012

J. Braz. Chem. Soc.

View full text Add to dashboard Cite

Neste trabalho relatamos uma síntese versátil de quatorze γ-lactonas análogas, dentre as quais nove são inéditas, a partir do furfural prontamente disponível. A atividade fitotóxica dos compostos sintetizados foi avaliada in vitro pela influência no crescimento de coleóptilos de trigo. A maior parte das porcentagens de inibição foi pequena e não diferenciou do controle após a terceira diluição (100 μmol L -1). Em geral, as lactonas α,β-insaturadas apresentaram melhor atividade que as saturadas. Os compostos mais ativos a 1000 μmol L -1 apresentaram inibições de 51, 68 e 76%. Os resultados indicam que, independentemente da saturação, a presença do anel γ-lactonônico é importante para a bioatividade, mas a sua presença não implica necessariamente boa potência.In this work we report a versatile synthesis of fourteen γ-lactones all structurally related, nine of which are novel compounds, accomplished from the readily available furfural. The phytotoxic activity of the synthesized compounds was evaluated in vitro by the influence on the growth of wheat coleoptiles. The percentages of inhibition were mostly small and not statistically different from control after the third dilution (100 μmol L -1 ). In general, α,β-unsaturated lactones presented better activities than the saturated ones. The most active compounds presented 51, 68 and 76% of inhibition in 1000 μmol L -1. The results indicate that regardless of saturation, the presence of the γ-lactone moiety is important for the bioactivity, but their presence has no implications with potency.

show abstract

“…QS inhibitors could also have synergistic effects with existing biocides. Vestby et al 35 showed that the effect of disinfectants on Salmonella in a biofilm was significantly enhanced when the biofilm was grown in the presence of a QS inhibitor. One way to utilize QS inhibitors might be their inclusion in functional coatings.…”

Section: Vtt No Species Induction Inhibition Inductionmentioning

confidence: 99%

Acyl Homoserine Lactone Production of Brewery Process Surface Bacteria

Priha

Juvonen

Tapani³

et al. 2011

Journal of the Institute of Brewing

View full text Add to dashboard Cite

The aim of this study was to find out whether the first bacterial colonizers of brewery process surfaces after washing produce acyl homoserine lactone (AHL) quorum sensing signalling molecules. Microbial attachment and biofilm formation was studied by mounting sterile uncoated and coated stainless steel coupons onto critical places of the filling machines in three breweries. In the present study 26 previously deposited bacterial strains, as well as approximately 2,300 colonies from 76 process surface samples, were screened using reporter bacteria Chromobacterium violaceum CV026 and Agrobacterium tumefaciens NTLR4. AHL-producing bacteria were detected both from process samples and among the previous isolates. From the process samples, up to 15% of the screened colonies produced AHL molecules. Production of long chain AHLs was more common than short chain AHLs. The identified AHL-producing isolates belonged to the genera Pseudomonas, Serratia, Hafnia, Rahnella, Enterobacter and Aeromonas, which all belong to commonly found primary colonizers of brewery process surfaces. The same microbial genera producing AHL molecules were found from different breweries. Brewery filling equipment is susceptible to microbial attachment and accumulation on surfaces. In the future, inhibition of quorum sensing could be one additional way of controlling biofilm formation.

show abstract

A synthetic furanone potentiates the effect of disinfectants on Salmonella in biofilm

Cited by 34 publications

References 35 publications

Commonly Used Disinfectants Fail To Eradicate Salmonella enterica Biofilms from Food Contact Surface Materials

Commonly Used Disinfectants Fail To Eradicate Salmonella enterica Biofilms from Food Contact Surface Materials

Synthesis and phytotoxicity of 4,5 functionalized tetrahydrofuran-2-ones

Acyl Homoserine Lactone Production of Brewery Process Surface Bacteria

Contact Info

Product

Resources

About