A switched capacitor oscillator with precision amplitude control and guaranteed start-up

Fleischer, P.E.; Ganesan, A.; Laker, K.R.

doi:10.1109/jssc.1985.1052358

Cited by 36 publications

(10 citation statements)

References 7 publications

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“…A nonlinear element (a simple comparator) within the feedback loop in Figure 7 is added to avoid the saturation of the active elements and then to keep sustained oscillations [29]. The oscillation amplitudes are controlled with precision thanks to this element.…”

Section: New Insights Into Cell Culture Technology 142mentioning

confidence: 99%

Remote Sensing of Cell-Culture Assays

Pérez¹,

Maldonado-Jacobi²,

Serrano-López³

et al. 2017

New Insights Into Cell Culture Technology

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This chapter describes a full system developed to perform the remote sensing of cellculture experiments from any access point with internet connection. The proposed system allows the real-time monitoring of cell assays thanks to bioimpedance measurement circuits developed to count the number of cell present in a culture. Cell-culture characterization is performed through the measurement of the increasing bioimpedance parameter over time. The circuit implementation is based on the oscillation-based test (OBT) methodology. Bioimpedance of cell cultures is measured in terms of the oscillation parameters (frequency, amplitude, phase, etc.) and used as empirical markers to carry out an appropriate interpretation in terms of cell size identiication, cell counting, cell growth, growth rhythm, etc. The device is capable of managing the whole sensing task and performs wireless communication through a Bluetooth module. Data are interpreted and displayed on a computer or a mobile phone through a web application. The system has its practical application in drug development processes, ofering a label-free, high-throughput, and high-content screening method for cellular research, avoiding the classical end-point techniques and a signiicant workload and cost material reduction.

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Section: New Insights Into Cell Culture Technology 142mentioning

confidence: 99%

Remote Sensing of Cell-Culture Assays

Pérez¹,

Maldonado-Jacobi²,

Serrano-López³

et al. 2017

New Insights Into Cell Culture Technology

View full text Add to dashboard Cite

show abstract

“…The oscillation frequency is equal to f 0 , while the sine-wave amplitude is determined by the center frequency gain of the filter and the peak values of the square-wave signal. An SC implementation of a BPF-based oscillator was proposed in [4], where the high-Q BPF was realized using the well-known E-type Fleischer and Laker biquad cell. The main limitation of this oscillator is that, in an SC implementation, a number of nonideal sources introduce large amount of noise at frequencies near the generated tone.…”

Section: Bpf-based Oscillatormentioning

confidence: 99%

“…Second-order SC bandpass filter. simulations were carried on using the second-order SC BPF presented in [4]. Figure 2(a) shows the spectrum of the square-wave signal at the output terminal of the comparator when the f s /f 0 ratio is equal to 10.075 rather than to its nominal value of 10.…”

Section: Bpf-based Oscillatormentioning

confidence: 99%

“…Figure 3 shows the SC filter structure, where φ 1 and φ 2 represent two non-overlapping clock phases derived from a master clock φ s having a period T s = 1/f s . As compared to the biquad cell in [4], the BP filter in Fig. 3 includes two extra capacitors, i.e., α and D 1 , connected in feedback around the first operational amplifier (op-amp) [7].…”

Section: Proposed Area-efficient Sc Oscillatormentioning

confidence: 99%

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A noise-shaping SC sine-wave oscillator

Dominguez

Carrillo

Duque-Carillo

et al. 2008

2008 IEEE International Symposium on Circuits and Systems (ISCAS)

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This paper describes an area-efficient switchedcapacitor sine-wave oscillator for on-chip analog testing. At the core of the oscillator is a bandpass filter (BPF) whose input signal is generated by using a noise-shaping modulation scheme. As a result, the spectral content of the input signal is improved with respect to a conventional BPF-based oscillator and, hence, the spurious-free dynamic range of the sine-wave signal is enhanced. Results from a 0.35-μm CMOS design are presented.

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“…It is particularly important to predict accordingly the oscillation parameters (frequency and amplitude), either analytically or by the means provided by simulation software [13], as well as to avoid any dependencies of these parameters on the active element saturation levels. The proposed solution relies on a nonlinear element (comparator) located at the feedback loop to guarantee self-maintaining oscillations [14], and a Band-Pass (BP) filter in the loop, as shown in Fig.1. Under this configuration an oscillation condition is generated for each oscillation state.…”

Section: Introductionmentioning

confidence: 99%

Cell-culture measurements using voltage oscillations

Maldonado

Huertas

Rueda

et al. 2016

2016 IEEE 7th Latin American Symposium on Circuits &Amp; Systems (LASCAS)

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Abstract-A comprehensive system for real-time monitoring of a set of cell-cultures using a Voltage Oscillation (VO) methodology is proposed. The main idea is to connect the bio-electrical elements (electrodes & cell-culture) in such a way that sequentially a suitable electrical oscillator, which only uses a DC power source, is built. Using the employed electrical models given in [1, 2], the attained oscillation parameters (frequency and amplitude) can be directly related to the biological test. A digital circuitry is developed to pick-up the experimental measurements, which are gathered and shown in real-time in a web application.

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A switched capacitor oscillator with precision amplitude control and guaranteed start-up

Cited by 36 publications

References 7 publications

Remote Sensing of Cell-Culture Assays

Remote Sensing of Cell-Culture Assays

A noise-shaping SC sine-wave oscillator

Cell-culture measurements using voltage oscillations

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