A switch strategy for the synthesis of C4-ethylamine indole and C7-aminoindoline via controllable carbon elimination
Bo-Sheng Zhang,
Bao-Jie Deng,
Yuan-Xin Zhi
et al.
Abstract:This manuscript describes a switchable synthesis of biologically active C4-ethylaminoindole and C7-aminoindoline scaffolds by controlling β-carbon elimination, utilizing aziridine as a C–H ethylamination reagent via C–N bond cleavage.
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