A “switch-on” fluorescence assay based on silicon quantum dots for determination of ascorbic acid

Ma, Fanghui; Luo, Junjun; Li, Xiaoqing; Liu, Shuping; Yang, Minghui; Chen, Xiang

doi:10.1016/j.saa.2020.119343

Cited by 27 publications

(11 citation statements)

References 33 publications

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“…The reported spectrofluorometric methods employed fluorescent dyes, or quantum dots as shown in Table 5 . These methods suffered from a number of limitations such as the complicated procedures [14] , [39] , [40] , the long reaction time [15] , the high temperature required [18] , [41] , [42] and the necessity for catalyst addition. Compared with these reported methods, our proposed method is easier, faster, and does not require heating or catalysis due to the instantaneous reaction and the high yield.…”

Section: Resultsmentioning

confidence: 99%

“…A number of techniques have been utilized for determination of ASC in different matrices, including UV/visible spectroscopy [9] , [10] , [11] , spectroflurometry [12] , [13] , [14] , [15] , [16] , [17] , [18] , high performance liquid chromatography [19] , [20] , and electrochemistry [21] , [22] , [23] . Compared with other techniques, spectroflurometry is more sensitive and more selective than UV/visible spectroscopy and does not require sophisticated instruments such as HPLC and LC/MS [24] , [25] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A highly sensitive switch-on spectrofluorometric method for determination of ascorbic acid using a selective eco-friendly approach

El‐Malla

Elattar

Kamal

et al. 2022

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A highly sensitive switch-on spectrofluorometric method for determination of ascorbic acid using a selective eco-friendly approach

El‐Malla

Elattar

Kamal

et al. 2022

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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“…Several fluorescent nonmetal dots are also exploited in MnO 2 NSs-based sensing applications. − Li et al constructed a nanocomposite of black phosphorus quantum dots (BPQDs) adhered on MnO 2 NSs for imaging and the determination of intracellular GSH levels . BPQDs were prepared by ultrasonication, followed by a hydrothermal method using bulk black phosphorus as a precursor.…”

Section: Sensing Applicationsmentioning

confidence: 99%

Review of 2D MnO₂ Nanosheets as FRET-Based Nanodot Fluorescence Quenchers in Chemosensing Applications

Hiremath

Banerjee

Chatterjee

2022

ACS Appl. Nano Mater.

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In the past decade, a variety of MnO 2 nanostructures have been used in chemosensing applications because of their unique redox properties, structural diversity, and broad absorption band, which makes them good energy acceptors. The most common strategy in Forster (or fluorescence) resonance energy transfer (FRET)-based chemosensing assays is to use low-dimensional fluorescent dots like carbon-based dots, metal dots, and even fluorescent dyes to form donor−acceptor pairs with 2D MnO 2 nanosheets (NSs). This review is a collection of the current library on fluorescent nanodots and MnO 2 NSs-based FRET conjugates as sensing platforms with a focus on highlighting the strategies involved in the detection of various analytes. Commonly, an analyte-triggered redox reaction results in the decomposition of MnO 2 NSs, leading to the release of fluorescent nanodots in solution for the turn-on detection of various reducing species. We intend to elaborately discuss the systematic upgradation of detection strategies involving fluorescent dots@2D MnO 2 NSs. Recently, a cascade of redox reactions was judiciously employed to target several bioanalytes involving a fluorescent dots@MnO 2 NSs FRET conjugate in a selective and sensitive manner. These sensing assays are categorized by the use of different fluorescent nanodots [carbon dots (CDs) and graphene quantum dots (GQDs), polymer dots, metal dots, etc.] with 2D MnO 2 NSs as FRET pairs in different sensing applications. Further, the analytes were categorized as reducing species, oxidants, enzymes, microbes, etc. The focus was paid to the sensing efficiency of the analytical tool. As a part of the study, a brief account of the synthesis of nanodots and MnO 2 NSs, their properties, and the FRET mechanism is also included. In a few cases, the sensing mechanism follows an inner filter effect without a prerequisite of the distance between the fluorophore and quencher units in the sensing of analytes, which are also covered in this collection. The available literature indicates a bright future for these FRET-based contemporary sensing strategies as environmentally benign, cost-effective, label-free techniques, which are discussed in the end.

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“…AA levels are associated with many diseases. Insufficient AA intake can lead to scurvy, while excessive AA intake can lead to kidney stones and stomach cramps [ 5 , 6 ]. Recent research has demonstrated the role of AA in stress-related disorders, inhibiting the development of cancer, and preventing and treating infection against COVID-19, making it urgent to analyze AA concentrations in food and clinical fields, especially for the performance measure of the techniques such as selectivity, sensitivity, and limit of detection in their utilization [ 4 , 7 , 8 , 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Ascorbic Acid Sensor Based on CdS QDs@PDA Fluorescence Resonance Energy Transfer

Chen

et al. 2022

Molecules

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An ascorbic acid (AA) sensor was constructed based on the fluorescence resonance energy transfer (FRET) between CdS quantum dots (CdS QDs) and polydopamine (PDA) to detect trace AA sensitively. FRET occurred due to the broad absorption spectrum of PDA completely overlapped with the narrow emission spectrum of CdS QDs. The fluorescence of CdS QDs was quenched and in the “off” state. When AA was present, the conversion of DA to PDA was hindered and the FRET disappeared, resulting in the fluorescence of CdS QDs in an “on” state. Importantly, the degree of fluorescence recovery of CdS QDs displayed a desirable linear correlation with the concentration of AA in the range of 5.0–100.0 μmol/L, the linear equation is y=0.0119cAA+0.3113, and the detection limit is 1.16 μmol/L (S/N = 3, n = 9). There was almost no interference with common amino acid, glucose and biological sulfhydryl small molecules to AA. Trace amount of AA in vitamin C tablets were determined and satisfactory results were obtained; the recoveries were observed to be 98.01–100.7%.

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A “switch-on” fluorescence assay based on silicon quantum dots for determination of ascorbic acid

Cited by 27 publications

References 33 publications

A highly sensitive switch-on spectrofluorometric method for determination of ascorbic acid using a selective eco-friendly approach

A highly sensitive switch-on spectrofluorometric method for determination of ascorbic acid using a selective eco-friendly approach

Review of 2D MnO₂ Nanosheets as FRET-Based Nanodot Fluorescence Quenchers in Chemosensing Applications

Ascorbic Acid Sensor Based on CdS QDs@PDA Fluorescence Resonance Energy Transfer

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A “switch-on” fluorescence assay based on silicon quantum dots for determination of ascorbic acid

Cited by 27 publications

References 33 publications

A highly sensitive switch-on spectrofluorometric method for determination of ascorbic acid using a selective eco-friendly approach

A highly sensitive switch-on spectrofluorometric method for determination of ascorbic acid using a selective eco-friendly approach

Review of 2D MnO2 Nanosheets as FRET-Based Nanodot Fluorescence Quenchers in Chemosensing Applications

Ascorbic Acid Sensor Based on CdS QDs@PDA Fluorescence Resonance Energy Transfer

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Review of 2D MnO₂ Nanosheets as FRET-Based Nanodot Fluorescence Quenchers in Chemosensing Applications