A Survey Of Local Preparation Methods And Quality Of Kunun-Zaki In Two Metropolitan Towns Of Northrn Nigeria

Egbere, O. J.; Luka, Joshua; Soo, JN; Zumbes, HI; Chollom, P; Henry, UI

doi:10.4314/gjpas.v14i4.16825

Cited by 2 publications

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“…"Kunun zaki" is produced all year round, and its consumption is fast spreading from the northern to the southern part of Nigeria. It is also cheaper and more satisfying than the carbonated beverages to the low-income earners in the society [12]. [13] reported several beneficial activities of LAB which include immunomodulatory, antiallergic, antimicrobial, antihypertensive, and antitumorigenic effects.…”

Section: Introductionmentioning

confidence: 99%

Preliminary Investigations on the Therapeutic Efficacy and Safety of Mixed Probiotic Lactic Acid Bacteria on Albino Rats Challenged with Shigella dysenteriae

Ibejekwe,

Egbere,

Dashen

et al. 2023

Advanced Gut & Microbiome Research

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This study investigates the potential of lactic acid bacteria (LAB) from the Nigerian beverage “kunun zaki” as alternative therapeutic agents against Shigella dysenteriae infections. In light of rising antibiotic resistance, the decline in probiotic usage prompted interest in LAB’s role in countering bacterial dysentery. Shigella dysenteriae, a significant cause of dysentery in developing nations, prompted this research which aims to carry out a preliminary investigation on the therapeutic efficacy and safety of mixed probiotic lactic acid bacteria on albino rats challenged with Shigella dysenteriae. Lactic acid bacteria, known for treating infections, were isolated from the beverage and tested against Shigella dysenteriae. The study employed 15 albino rats for in vivo trials, inducing diarrhea and treating with Lactococcus lactis and Lactobacillus brevis separately (T1 and T2) and combined in a 1 : 1 ratio (T3). Clinical parameters were observed before and after treatment. This revealed that L. lactis and L. brevis administration lowered rectal temperature from an average of 42°C caused by infection to 36.5°C. Stool consistency improved from light brown loose to dark brown semisolid, signifying reduced diarrhea. Bacteriological analysis displayed significant reduction ( p < 0.05 ) in Shigella counts in rat intestines across all treatments— 220 ± 2.88 C F U / g to 19.00 ± 1.77 C F U / g , 8.33 ± 0.88 C F U / g , and 65.00 ± 2.88 C F U / g for T1, T2, and T3, respectively. The mixed LAB treatment was notably effective. Lactic acid bacteria counts increased significantly in Shigella-treated rats versus the positive control. Hematology and liver function parameters showed no significant differences between treatments and untreated controls. Lactic acid bacteria from “kunun zaki” exhibited curative potential, individually or combined, against Shigella dysenteriae. These lactic acid bacteria also positively influenced gut microbiota in Shigella-infected albino rats.

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Section: Introductionmentioning

confidence: 99%

Preliminary Investigations on the Therapeutic Efficacy and Safety of Mixed Probiotic Lactic Acid Bacteria on Albino Rats Challenged with Shigella dysenteriae

Ibejekwe,

Egbere,

Dashen

et al. 2023

Advanced Gut & Microbiome Research

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show abstract

“…The hand has been recognized as the major carrier of many germs of fecal origin and body flora through the mouth, nose, eyes, etc. into the human body resulting in infectious diseases such as the current pandemic Coronavirus, diarrhea, cholera, Ebola, Lassa fever, flu, hepatitis and the likes (Greger, 2007;Gould et al, 2017;Jefferson et al, 2011;Ngene et al, 2020;Egbere et al, 2008). Hand washing has an age-long recognition among religious and cultural practices of the world.…”

Section: Introductionmentioning

confidence: 99%

Assessment of the hand hygiene status of internally displaced persons in Jos and environs, Nigeria

Egbere¹,

Odu²,

Ngene³

et al. 2020

Afr. J. Microbiol. Res.

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A Survey Of Local Preparation Methods And Quality Of Kunun-Zaki In Two Metropolitan Towns Of Northrn Nigeria

Cited by 2 publications

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Preliminary Investigations on the Therapeutic Efficacy and Safety of Mixed Probiotic Lactic Acid Bacteria on Albino Rats Challenged with Shigella dysenteriae

Preliminary Investigations on the Therapeutic Efficacy and Safety of Mixed Probiotic Lactic Acid Bacteria on Albino Rats Challenged with Shigella dysenteriae

Assessment of the hand hygiene status of internally displaced persons in Jos and environs, Nigeria

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