A Survey of Hospital Acquired Infections in Obafemi Awolowo University Teaching Hospital, Ile-Ife

Onipede, Anthony; Oluyede, CO; Aboderin, AO; Zailani, SB; Adedosu, AM; Oyelese, A O; Badmus, TA; Ikem, IC; Balogun, CO; Olafimihan, KF

doi:10.4314/ajcem.v5i1.7363

Cited by 13 publications

(18 citation statements)

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“…This type of infection occurs in 5% of all acute care hospitalization in the United State and has been reported to be responsible for the death of one out of every five thousand patients attending an American hospital [17] . In Nigeria, the rate of nosocomial infection ranges between 2.7%-3.8% [18,19] , but 4.0% at OOUTH before this study. This calls for looking at every possible measure to control the rise including (among other investigations) examining the quality of indoor air of the hospital wards and units.…”

Section: Discussionmentioning

confidence: 70%

Microbiological assessment of indoor air of a teaching hospital in Nigeria

Awosika

Olajubu

Amusa

2012

Asian Pacific Journal of Tropical Biomedicine

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Section: Discussionmentioning

confidence: 70%

Microbiological assessment of indoor air of a teaching hospital in Nigeria

Awosika

Olajubu

Amusa

2012

Asian Pacific Journal of Tropical Biomedicine

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“…This is particularly of significant interest in developing country where hospital acquired infection programs need optimum strengthening to reduce the incidence of catheter-associated UTI (Onipede et al, 2004) and to avoid unwarranted treatment of asymptomatic bacteriuria. In support of this point of view, this study observed that several key information that are essential to infection control activities were not documented.…”

Section: Discussionmentioning

confidence: 99%

Urinary Pathogens and Their Antimicrobial Susceptibility in Patients with Indwelling Urinary Catheter

Onipede¹,

Oyekale²,

Olopade³

et al. 2010

Sierra Leone j. biomed. res.

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The indwelling urinary catheter (IUC) is the most significant risk factor for developing nosocomial urinary tract infections (UTIs). In order to determine the spectrum of bacterial etiology and antibiotic resistance pattern of uropathogens causing catheter associated UTI, a convenient sample size of ninety-two (92) patients on urethral catheter was investigated. Ethical approval for the study was obtained from the OAUTHC research and ethical committee. Catheter stream urine samples were obtained from all patients and cultured on appropriate culture media. Suspected isolates were identified by a combination of standard tests and using MICROBACT GNA12A/B/E. Susceptibility of the isolates against thirteen (13) antibiotics was performed by the disc diffusion method. Significant bacteriuria was observed in 60.9% (56) catheter specimen urine (CSU) received, while 39.1% (36) were culture negative. Of the 56 positive culture, the predominant organisms were Klebsiella oxytoca, 28.6 %( 16), Proteus vulgaris, 23.2% (13) and Staphylococcus aureus, 12.5% (7). Overall, the antimicrobial susceptibility results showed that all the isolates were highly resistant to the antibiotics tested. Over 50% resistance was recorded for trimethoprim/sulfamethoxazole, gentamicin and amoxicillin/clavulanic acid. More than 25% of the isolates were resistant to nitrofurantoin. This study indicates that catheter stream UTI caused by multiply resistant bacteria are common in our hospital. There is a need to establish standard guidelines on the care of catheter for all units in the hospital with a view to preventing nosocomial infections associated with the use of the catheter in patients. We also advocated prudent use of antibiotics. Key words: Antibiotic resistance, Urinary catheter, Uropathogens, Urinary tract infection Received 27 March 2010/ Accepted 1 June 2010 INTRODUCTIONUrinary tract infections (UTIs) are the most common infections found in the hospital as well as long-term care setting. The indwelling urinary catheter (IUC) is the most significant risk factor for developing catheter-associated urinary tract infections (CAUTIs). The risk of acquiring a urinary tract infection depends on the method and duration of catheterisation, the quality of catheter care, and host susceptibility among others. Several studies have indicated that between 75 and 80% of all healthcare associated UTIs follow the insertion of a urinary catheter (Bryan and

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“…Whereas gram positive organisms were the predominant organisms involved in these infections, gram negative organisms are now being isolated at an increasing rate 25 . This shift may result from the greater complexity of the structure of the gram negative bacteria cell wall that made it to have intrinsic resistance to most antibacterial agents in use in the hospitals.…”

Section: Discussionmentioning

confidence: 99%