A Survey of Hodgkin's Disease and Lymphosarcoma in Bone

Vieta, John O.; Friedell, Hymer L.; Craver, Lloyd F.

doi:10.1148/39.1.1

Cited by 56 publications

(5 citation statements)

References 14 publications

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“…1,2 At autopsy, as might be expected, the incidence is higher than is evident clinically. Magnetic resonance imaging (MRI) improves the sensitivity of diagnosis of the epidural mass and accompanying bone marrow in®ltration.…”

Section: Introductionmentioning

confidence: 69%

“…10 Spinal foci of disease was found in 49% of 257 patients with HD and lymphosarcoma at autopsy, whereas radiologically demonstrable lesions were only present in 14.8% of the cases. 2 MRI is a noninvasive procedure superior in the evaluation of the localization and the extent of a paraspinal soft tissue mass. Virtually the whole of the spinal canal is demonstrated.…”

Section: Discussionmentioning

confidence: 99%

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Stage IV Hodgkin's Disease presenting with spinal epidural involvement and cauda equina compression as the initial manifestation: Case report

et al. 1997

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Hodgkin's disease very rarely presents clinically, initially with a paraspinal mass, but this should be considered in the di erential diagnosis. A patient presenting with back pain was diagnosed to have Stage IV Hodgkin's disease. MRI revealed an extradural and intraspinal soft tissue mass with bone in®ltration. The importance of MRI in the early evaluation of a paraspinal mass and in determining the extent of the disease is emphasized.

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Section: Introductionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Stage IV Hodgkin's Disease presenting with spinal epidural involvement and cauda equina compression as the initial manifestation: Case report

et al. 1997

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“…The frequency of skeletal involvement in lymphosarcoma is probably greater than the reported 8 to 11 per cent depending on how meticulously it is searched for (Gall and Mallory, 1942;Craver and Copeland, 1934;Vieta, Friedell, and Craver, 1942;Hish and Pinkel, 1967;Rosenberg, Diamond, Jaslowitz, and Craver, 1961;Sugarbaker and Craver, 1940). The most common sites for skeletal lymphosarcoma are the bones of the trunk and proximal extremities (Coles and Schulz, 1948;Johnston and Liggett, 1964).…”

Section: Discussionmentioning

confidence: 99%

Lymphosarcomatous arthropathy.

Martin¹,

Bennett²,

Hughes³

et al. 1973

Annals of the Rheumatic Diseases

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; normal urea and electrolytes; phosphorus 1 9 mN, alkaline phosphatase 10 K-A. Ltnits, albumin 2 9 g./100 ml.; electrophoretic strip-raised alpha-cholesterol 159 mg./ 100 ml, urine analysis normal. 2-globulin. Uric acid 4 6 mg./l00 ml, calcium 4-7 mN, Radiographs showed multiple radiolucent areas at the Accepted for publication August 18, 1972. lower end of the left tibia (Fig. 1) and in the small bones

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“…Perttala and Kijanen [2] encountered bony involvement in 48 cases in a series of 453 cases (10.6%). Solitary or multifocal bone involvement in the absence of visceral or nodal disease at presentation is particularly uncommon, occurring in less than 1% of cases [3,4].…”

Section: Discussionmentioning

confidence: 99%

Primary multifocal skeletal Hodgkin’s disease confined to bone

et al. 1995

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Clinical informationThe patient, a 63-year-old man, presented complaining of severe pain in the left thigh and marked weight loss. Haematological screening tests revealed a mild leucocytosis (WCCr = 16x103) and a markedly elevated erythrocyte sedimentation rate at 90 mm/h. An anteroposterior radiograph of the left hip revealed the presence of focal lyric bone destruction in the neck of the lemur (Fig. 1) corresponding to a site of increased uptake at scintigraphy (Fig. 2). Magnetic resonance imaging (MRI) confirmed the presence of marrow infiltration both in the neck of the left femur and the right iliac wing, which was of low signal on Tl-weighted spin echo sections and of high signal on gradient echo T2-weighted FISP sequences (Fig. 3). Computed tomography (CT) of thorax and abdomen, undertaken to search for an occult primary source, revealed the presence of further lytic deposits within the lumbar vertebral bodies (Fig. 4). No associated mediastinal, intra-abdominal, retrocrural or retroperitoneal nodes were identified. Suspecting the presence of bony metastases, biopsy of the lesion in the left upper femur was undertaken under fluoroscopy.

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A Survey of Hodgkin's Disease and Lymphosarcoma in Bone

Cited by 56 publications

References 14 publications

Stage IV Hodgkin's Disease presenting with spinal epidural involvement and cauda equina compression as the initial manifestation: Case report

Stage IV Hodgkin's Disease presenting with spinal epidural involvement and cauda equina compression as the initial manifestation: Case report

Lymphosarcomatous arthropathy.

Primary multifocal skeletal Hodgkin’s disease confined to bone

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