A Survey of Deep Learning Methods for Estimating the Accuracy of Protein Quaternary Structure Models
Xiao Chen,
Jian Liu,
Nolan Park
et al.
Abstract:The quality prediction of quaternary structure models of a protein complex, in the absence
of its true structure, is known as the Estimation of Model Accuracy (EMA). EMA is useful for
ranking predicted protein complex structures and using them appropriately in biomedical research,
such as protein-protein interaction studies, protein design, and drug discovery. With the advent
of more accurate protein complex (multimer) prediction tools, such as AlphaFold2-Multimer and
ESMFold, the estimation of the accuracy of… Show more
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