A Surface Plasmon Biosensor Based on a D-Shaped Microstructured Optical Fiber With Rectangular Lattice

Lü, Peng; Shi, Fukun; Zhou, Guiyao; Ge, Shu; Hou, Zhipeng; Xia, Changming

doi:10.1109/jphot.2015.2488278

Cited by 53 publications

(26 citation statements)

References 28 publications

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“…This paper is the pioneer to discuss and to apply graphene to SPR sensor device, and also graphene when compared with regular metal layer can not only produce the SPR effect but due to its high surface area ratio it can also contact the analyte. This strategy has the advantages of rapid, real‐time detection, enhanced sensitivity, and also the amount of analyte required for the analysis is less, etc., and also it discovered that the tapered optical fiber, side‐polished fiber, etc., can also add up to the good performance of the sensing device . Graphene combined SPR sensor devices have some advantages like SPR sensors but also further improve the sensitivity and optimize detection range and resonance wavelength .…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Graphene and Graphene‐Based Materials in Biomedical Science

Swetha

Manisha

Prasad

2018

Part & Part Syst Charact

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Graphene and its composite materials are very important in many disciplines of science and have been used enormously by researchers since their discovery in 2004. These are a new group of compounds, and are also wonderful model systems for quantum behavior studies. Their properties like exceptional conductivity, biocompatibility, surface area, mechanical strength, and thermal properties make them rising stars in the scientific community. Graphene and its composite compounds are utilized widely in different medical applications, for example, biosensing of biological compounds responsible for disease development, bioimaging of various cells, tissues, microorganisms, animal models, etc. In addition, they are used for enhancing and supporting the stem cell differentiation, i.e., regenerative medicine for regeneration studies of various human organs, tissue engineering in biology for the development of carrier materials, as well as in bone reformation. This review focuses on the modification procedure involved in the fabrication of graphene‐based biomaterials for various applications and recent developments in research related to graphene and graphene‐based materials in biosensing, optical sensing, gas sensing, drug, gene, protein delivery, tissue engineering, and bioimaging. In addition, the potential toxicological effects of graphene‐based biomaterials are discussed.

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Section: Biomedical Applicationsmentioning

confidence: 99%

Graphene and Graphene‐Based Materials in Biomedical Science

Swetha

Manisha

Prasad

2018

Part & Part Syst Charact

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“…In another recent paper [5], a Dshaped hollow core microstructured optical fiber-based surface plasmon resonance sensors is proposed: in this case λ S and S A values of 2900 nm/RIU and 120 RIU -1 , respectively, when n a is varied from 1.33 to 1.34 have been reported. In another recent paper [6], an alternative plasmon D-shaped microstructured biosensor with rectangular lattice has been presented: the largest value of figure of merit (FOM) [13] is 478.3 RIU -1 and the lowest value of the resonance spectral width δλ is 13.6 nm for the core guided mode; then for n a > 1.398, a record value of λ S > 7481 nm RIU -1 has been obtained, although multiple resonance peaks and large spectral width can deteriorate the signal-to-noise ratio.…”

Section: Introductionmentioning

confidence: 95%

“…Microstructured optical fiber-based plasmonic devices have attracted a large interest [1][2][3][4][5][6][7][8] for their application in chemical and biochemical sensing because of their large sensitivity combined with the possibility to easily tailor their properties by varying the geometry of the photonic crystal fiber. For instance, by changing the hole number and position the phase matching [1] or the loss matching [2][3] conditions between the fundamental HE 11 core mode and a plasmon mode can be achieved.…”

Section: Introductionmentioning

confidence: 99%

Simulation of the Sensing Performance of a Plasmonic Biosensor Based on Birefringent Solid-Core Microstructured Optical Fiber

2016

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“…Then they determined the highest sensitivity to be 7381.0nm/RIU in the refractive index environment of 1.40-1.42. Last but not least, Peng et al [21] proposed a D-shaped MOF SPR senor, which consists of a rectangular lattice with two special large air holes. Based on the analysis of the mode coupling characteristics, the sensing performance dependence of fiber birefringence and the two large leaky channels is revealed.…”

Section: Introductionmentioning

confidence: 99%

Surface plasmon resonance biosensor based on gold-coated side-polished hexagonal structure photonic crystal fiber

et al. 2017

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The refractive index sensing characteristics of the side-polished photonic crystal fiber (PCF) surface plasmon resonance (SPR) sensor are detailed investigated in this paper. We used the finite element method (FEM) to study the influences of the side-polished depth, air hole size, lattice constant, and the refractive index (RI) of the PCF material on sensing performance. The simulation results show that the side-polished depth, air hole size, lattice pitch have significant influence on the coupling strength between core mode and surface plasmon polaritons (SPPs), but have little influence on sensitivity; the coupling strength and sensitivity will significant increase with the decrease of RI of the PCF material. The sensitivity of the D-shaped PCF sensor is obtained to be as high as 21700 nm/RIU in the refractive index environment of 1.33-1.34, when the RI of the PCF material is controlled at 1.36. It revealed a new method of making ultra-high sensitivity SPR fiber sensor. Then we experimental demonstrated a SPR refractive sensor based on the side-polished single mode PCF and investigated the sensing performance. The experimental results of the plasmon resonance wavelength sensitivity agree well with the theoretical results. The presented gold-coated D-shaped PCF SPR sensor could be used as a simple, cost-effective, high sensitivity device in bio-chemical detection.

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A Surface Plasmon Biosensor Based on a D-Shaped Microstructured Optical Fiber With Rectangular Lattice

Cited by 53 publications

References 28 publications

Graphene and Graphene‐Based Materials in Biomedical Science

Graphene and Graphene‐Based Materials in Biomedical Science

Simulation of the Sensing Performance of a Plasmonic Biosensor Based on Birefringent Solid-Core Microstructured Optical Fiber

Surface plasmon resonance biosensor based on gold-coated side-polished hexagonal structure photonic crystal fiber

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