Abstract. Elevation scans across geomagnetic mid latitudes by the incoherent scatter radar at Millstone Hill captured the ionospheric response to the ®ring of the Space Shuttle Challenger OMS thrusters near the peak of the F layer on July 30, 1985. Details of the excitation of airglow and the formation of an ionospheric hole during this event have been reported in an earlier paper by Mendillo et al.. The depletion (factor $2) near the 320 km Shuttle orbital altitude persisted for $35 min and then recovered to near normal levels, while at 265 km the density was reduced by a factor of $6; this signi®cant reduction in the bottomside F-region density persisted for more than 3 hours. Total electron content in the vicinity of the hole was reduced by more than a factor of 2, and an oscillation of the F-region densities with 40-min period ensued and persisted for several hours. Plasma vertical Doppler velocity varied quasiperiodically with a $80-min period, while magnetic ®eld variations observed on the ®eld line through the Shuttleburn position exhibited a similar $80-min periodicity. An interval of magnetic ®eld variations at hydromagnetic frequencies ($95 s period) accompanied the ionospheric perturbations on this ®eld line. Radar observations revealed a downward phase progression of the 40-min period density enhancements of A1.12°km A1 , corresponding to a 320-km vertical wavelength. An auroral-latitude geomagnetic disturbance began near the time of the Spacelab-2 experiment and was associated with the imposition of a strong southward IMF Bz across the magnetosphere. This created an additional complication in the interpretation of the active ionospheric experiment. It cannot be determined uniquely whether the ionospheric oscillations, which followed the Spacelab-2 experiment, were related to the active experiment or were the result of a propagating ionospheric disturbance (TID) launched by the enhanced auroral activity. The most reasonable conclusion is that the ionospheric oscillations were a result of the coincident geomagnetic disturbance. The pronounced depletion of the bottomside ionosphere, however, accentuated the oscillatory behavior during the interval following the Shuttle OMS burn.