A successfully resected case of left trisectionectomy with arterio-portal combined resection for advanced cholangiocarcinoma

Nanashima, Atsushi; Imamura, Naoya; Hiyoshi, Masahide; Yano, Koichi; Hamada, Takeomi; Chiyotanda, Teru; Nagatomo, Kenzo; Hamada, Rouko; Ito, Hiroshi

doi:10.1016/j.ijscr.2018.10.036

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…Alanine amino transferase and AST can be used to evaluate the extent of hepatocellular injury, with the elevation of ALT being roughly parallel to the degree of cellular injury[ 18 , 19 ]. The vast majority of TBIL in the human body comes from aging red blood cells, which are metabolized by the liver.…”

Section: Discussionmentioning

confidence: 99%

Effect of hepatic artery resection and reconstruction on the prognosis of patients with advanced hilar cholangiocarcinoma

Li¹,

Bie²,

Guo³

et al. 2022

WJGO

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BACKGROUND Hilar cholangiocarcinoma (HC) is a good adaptation certificate of hepatic arterectomy, and hepatic arterectomy is conductive to the radical resection of cholangiocarcinoma, which simplifies the operation and helps with a combined resection of the peripheral portal tissue. With continuous development of surgical techniques, especially microsurgical technique, vascular invasion is no longer a contraindication to surgery in the past 10 years. However, hepatic artery reconstruction after hepatic arterectomy has been performed to treat liver tumor in many centers with better results, but it is rarely applied in advanced HC. AIM To determine the prognosis of patients with advanced HC after hepatic artery resection and reconstruction. METHODS A total of 98 patients with HC who underwent radical operation in our hospital were selected for this retrospective analysis. According to whether the patients underwent hepatic artery resection and reconstruction or not, they were divided into reconstruction ( n = 40) and control ( n = 58) groups. The traumatic indices, surgical resection margin, liver function tests before and after the operation, and surgical complications were compared between the two groups. RESULTS Operation time, blood loss, hospital stay, and gastrointestinal function recovery time were higher in the reconstruction group than in the control group ( P < 0.05); The R0 resection rates were 90.00% and 72.41% in the reconstruction and control groups, respectively ( P < 0.05). Serum alanine aminotransferase was lower in the reconstruction group on day one and three postoperatively, whereas serum aspartate aminotransferase was lower on the third day ( P < 0.05). Preoperatively, the Karnofsky performance status scores were similar between the groups ( P > 0.05), but was higher in the reconstruction group ( P < 0.05) two weeks postoperatively. There was no difference in the complication rate between the two groups (27.50% vs 32.67%, P > 0.05). Two-year survival rate (42.50% vs 39.66%) and two-year survival time (22.0 mo vs 23.0 mo) were similar between the groups ( P > 0.05). CONCLUSION Radical surgery combined with reconstruction after hepatic artery resection improves R0 resection rate and reduces postoperative liver injury in advanced HC. However, the operation is difficult and the effect on survival time is not clear.

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Section: Discussionmentioning

confidence: 99%

Effect of hepatic artery resection and reconstruction on the prognosis of patients with advanced hilar cholangiocarcinoma

Li¹,

Bie²,

Guo³

et al. 2022

WJGO

View full text Add to dashboard Cite

show abstract

Vascular reconstruction provides short-term and long-term survival benefits for patients with hilar cholangiocarcinoma: A retrospective, multicenter study

Huang,

Xu,

Zhang

et al. 2024

Hepatobiliary & Pancreatic Diseases International

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A successfully resected case of left trisectionectomy with arterio-portal combined resection for advanced cholangiocarcinoma

Abstract: HighlightsIn case of cholangiocarcinoma invading hilar vessels, adequate simulations and expert skills are required to achieve R0 resection.

Cited by 2 publications

References 15 publications

Effect of hepatic artery resection and reconstruction on the prognosis of patients with advanced hilar cholangiocarcinoma

Effect of hepatic artery resection and reconstruction on the prognosis of patients with advanced hilar cholangiocarcinoma

Vascular reconstruction provides short-term and long-term survival benefits for patients with hilar cholangiocarcinoma: A retrospective, multicenter study

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