Laparoscopic cholecystectomy is one of the most commonly performed surgeries worldwide and has only recently achieved a perioperative predictive score. This study aims to document our experience as a tertiary care hospital regarding the use of the same. 250 patients were considered in a prospective observational study, subsequently recording the intraoperative findings and postoperative complications based on G10 scoring put forward by the WSES based on the Sugrue study. They were classified as easy, moderate, difficult, and extremely difficult. The mean operative time was 48.58 min (range 30 to 190). The conversion rate was 2%. A p value of <0.0001 shows G10 scoring is significantly related to open conversion. Overall, 19 (7.60%) patients were found to have a difficult or extreme degree of operative difficulty as judged by a G10 score of 5 or greater. A significant relationship was found with respect to bile duct injury, biliary fistula, vessel injury, abscess formation, and readmission in view of G10-based scoring difficulty. Validation and widespread adaptation may provide a standard for understanding and improving care and enable more standardization in global comparisons of care for cholecystectomy. This study is a single institution experience validating the significance of intraoperative scoring for biliary disease management.