A study to compare continuous epidural infusion and intermittent bolus of bupivacaine for postoperative analgesia following renal surgery

Comparison of analgesic effects of programmed intermittent epidural bolus and continuous epidural infusion after total knee arthroplasty

“…This can explain why PIEB has a better analgesic effect than CEI. Virmani et al [ 3 ] reported that IEB has more fluctuation, so that CEI is appropriate. However, in that study, the interval of boluses was 3 h, which could disturb the constant analgesic effect of IEB.…”

Comparative Evaluation of Haemodynamic Effects of Continuous Versus Intermittent Epidural Injections of Bupivacaine with Fentanyl for Major Gynaecological Surgeries

“…This can lead to blood pressure variability [17,18]. Virmani et al [23] found no significant fall in blood pressure in their study that compared continuous infusion of 0.166% bupivacaine at the rate of 5 ml/hr and 3 hourly bolus doses of 15 ml of same dose of bupivacaine for postoperative analgesia following renal surgery. They reported that this may be due to the low concentration of bupivacaine and continuous infusion of intravenous fluid given to the patients throughout the study period.…”

Comparison of continuous epidural infusion of 0.125% ropivacaine with 1μg/ml fentanyl versus 0.125% bupivacaine with 1μg/ml fentanyl for postoperative analgesia in major abdominal surgery

“…concluded that continuous infusion as compared to intermittent boluses provided better pain relief at rest, on movement and provided sustained degree of analgesia. [ 9 ] Wheatley et al . analyzed four studies and reported that the group that received a combination of local anesthetic and lipophilic opioid as a continuous epidural infusion had much better dynamic relief as compared to groups that received either drug alone.…”