A study on the therapeutic efficacy of Cassia alata, Linn. leaf extract against Pityriasis versicolor

Damodaran, S; Venkataraman, S.

doi:10.1016/0378-8741(94)90018-3

Cited by 43 publications

(19 citation statements)

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“…Trabalhos recentes baseados em morfologia floral têm confirmado essa divisão (Boonkerd et al, 2005). O gênero Cassia sensu lato possui um longo histórico de importância econômica, sobretudo como plantas medicinais (Boonkerd et al, 2005) A espécie Senna alata apresenta propriedades terapêuticas; na Índia, todas as partes da planta são utilizadas nos sistemas de medicina ayurvedica, unani e alopática (Damodaran & Venkataraman, 1994). Em muitos países, suas folhas, cascas, flores e raízes podem ser utilizadas na medicina popular por suas propriedades anti-herpética, antifebrífuga, antianêmica, antiblenorrágica, antinefrítica, antídota, antimicótica, diurética, parasiticida, laxante e contra doenças de pele (Awal et al, 2004;Ordoñez et al, 2004;Barrese Pérez et al, 2005;Pieme et al, 2006;Plantamed, 2007).…”

Section: Introductionunclassified

Prospecção química de compostos produzidos por Senna alata com atividade alelopática

et al. 2010

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RESUMO -Senna alata é uma espécie daninha frequente em pastagens da região amazônica. Suas folhas apresentam propriedades medicinais capazes de influenciar a germinação e o desenvolvimento de outras plantas. Objetivou-se neste estudo a prospecção química e a avaliação da atividade alelopática dos compostos presentes nas folhas de S. alata. O material vegetal foi seco, triturado e submetido à extração exaustiva, com solução água:metanol (3:7). O extrato obtido foi então fracionado por coluna cromatográfica por via úmida. As frações mais puras foram submetidas à espectroscopia de Ressonância Magnética Nuclear, para determinação das fórmulas estruturais das moléculas. Na avaliação dos efeitos das substâncias químicas isoladas, utilizaram-se as concentrações de 50, 100, 150 e 200 ppm, tendo como eluente solução hidrometanólica (3:7 v/v). As frações foram adicionadas em placas de Petri e seus efeitos avaliados sobre a germinação de sementes e o alongamento da radícula e hipocótilo de três espécies daninhas de áreas de pastagens: Mimosa pudica, Senna obtusifolia e a própria S. alata. Os compostos com atividade alelopática encontrados em folhas de S. alata pertencem à classe dos flavonoides glicosilados, cujo núcleo aromático é um kaempferol, e causaram maior inibição sobre o crescimento da radícula e sobre a germinação de S. obtusifolia e M. pudica. Já os efeitos autotóxicos desse composto são pouco significativos para o desenvolvimento da plântula e nulos sobre a germinação.Palavras-chave: Leguminosae, aleloquímicos, RMN, flavonoides glicosilados, kaempferol.ABSTRACT -Senna alata is a weed species frequently found in pastures of the Amazonian region and whose leaves have medicinal properties. This study aimed to carry out a chemical prospecting and evaluation of the allelopathic activity of the compounds present in S. alata leaves. The plant material was dried, ground, and submitted to exhaustive extraction with water/methanol (3:7) solution. The crude extract obtained was fractioned by wet chromatography column. The purest fractions were submitted to Nuclear Magnetic Resonance Spectroscopy to determine their structures. To evaluate the effects of the isolated chemical substances, concentrations of 50, 100, 150 and 200 ppm were used in water/methanol solvents (3:7). The fractions were placed on Petri dishes and their effects were evaluated on seed germination and radicle and hypocotyl elongation of three pasture weeds: Mimosa pudica, Senna obtusifolia, and Senna alata itself. The compounds with allelopathic activity found in S. alata leaves belong to the flavonoid glycoside class, whose aromatic core is a kaempferol causing major inhibition on radicle elongation and germination of S. obtusifolia and M. pudica. The auto toxic effects of this compound are not very significant for seedling development and null for germination.

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Section: Introductionunclassified

Prospecção química de compostos produzidos por Senna alata com atividade alelopática

et al. 2010

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“…It is belongs to the family Fabaceae. It is native to the Amazon Rain forest and can be found in Peru, Brazil, French Guiana, Guyana, Suriname, Venezuela and Colombia [2]. Found in many habitats, preferring disturbed, rather open vegetation such as roadsides, river banks, rain forest edges, lake shores, pond and ditch margins, open forest, orchards and around villages.…”

Section: Introductionmentioning

confidence: 99%

Studies on the antioxidant activity of ethanol extract of Cassis alata using FT-IR, HPLC and GC-MS analysis

Sujatha¹,

Asokan²

2017

Int. J. Adv. Res. Biol. Sci.

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The aim of the present investigation is to screening of phytochemical constituents for its free radical scavenging activity of ethanol extract of Cassia alata leaves. The preliminary screening was carried out by standard chemical method. It evidenced that the presence of phytochemicals such as alkaloids, carbohydrate, phenols, tannins, falvanoids, steroids, protein and sugar in the ethanol extract. Various functional groups like alcohols, phenols, carboxylic acid and nitro groups were associated with the extract were characterized using Fourier transform infrared spectroscopy (FTIR). A few common compounds available in the extract were identified by Gas chromatography -Mass spectrum (GC-MS) analysis. The DPPH free radical scavenging activity and 50 % inhibitory concentration (IC 50 ) was calculated and compared with the standard synthetic drug BHT. The IC 50 value of leaf extract was found to be 24.56 µg/ml respectively. This study revealed that C. alata ethanol extract of leaves has alternative drugs for free radical it could be acted as a novel source of free radical scavengers.

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“…The activity of combination of the extracts was heat stable and worked at acidic pH. A 10-year human study indicated that the leaf extract could be reliably used as an herbal medicine to treat Pityriasis versicolor, a yeast fungus that causes skin disease (Damodaran and Venkataraman 1994 ). The leaf extract had no side effects.…”

Section: In-vitro Studies Leaf Extractsmentioning

confidence: 99%

Senna alata

Lim¹

2013

Edible Medicinal and Non-Medicinal Plants

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A study on the therapeutic efficacy of Cassia alata, Linn. leaf extract against Pityriasis versicolor

Cited by 43 publications

References 2 publications

Prospecção química de compostos produzidos por Senna alata com atividade alelopática

Prospecção química de compostos produzidos por Senna alata com atividade alelopática

Studies on the antioxidant activity of ethanol extract of Cassis alata using FT-IR, HPLC and GC-MS analysis

Senna alata

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