A study on the effects of the Qihuang Needle therapy on patients with Parkinson's disease

Abstract

ObjectiveThis study aimed to evaluate the effectiveness of the Qihuang Needle (QHN) in treating Parkinson's disease (PD).Design, setting, and participantsThe trial was an 8-week randomized clinical trial (4 weeks of treatment followed by 4 weeks of follow-up) conducted from January 2021 to July 2022 in outpatient settings at three clinical sites in Guangzhou, China. Thirty-four participants with PD were diagnosed based on the diagnostic criteria formulated by the brain bank of the British Parkinson's Disease Society in 1992.InterventionsPatients in the treatment and control groups received six sessions within 4 weeks of the QHN therapy or the sham acupuncture therapy (two times per week for the first two consecutive weeks and one time per week for the following two consecutive weeks).Main outcomes and measuresThe primary outcome measure was the change in the Parkinson's Disease Rating Scale-Part III Motor Examination (UPDRS III) between baseline and 8 weeks after treatments. Secondary outcome measures were the Non-Motor Symptoms Scale for Parkinson's Disease (NMSS) and Parkinson's Disease Daily Quality of Life-39 (PDQ-39). Real-time shear wave elastography (SWE) was assessed for each patient at baseline and during the 4-week period as the third outcome measure.ResultsA more significant reduction of UPDRS III score, PDQ-39, NMSS, and SWE was observed in the QHN group than in the sham acupuncture group.ConclusionsThe QHN therapy consistently demonstrated superiority and produced clinically meaningful benefits in reducing motor and non-motor symptoms, as well as significantly improving muscle stiffness, in patients with PD.

Oscillation-Specific Nodal Differences in Parkinson’s Disease Patients with Anxiety

“…An informed consent form was signed by all PD patients and healthy control (HC), and all procedures were conducted in accordance with the Declaration of Helsinki and the ethical standards of the Institutional Research Board. In accordance with British Parkinson’s Disease Society criteria, senior neurosurgeons diagnosed PD [ 19 ]. Information regarding patient demographics (including age, sex, and education) and clinical assessments, such as Hoehn-Yahr stage (H-Y), duration of disease, levodopa and equivalent dose (LED).…”