A Study on the Clinical Profiles of Patients With Cerebrovascular Accident (Stroke) in a Tertiary Care Hospital in Jharkhand

Kumar, Mukesh; Kumar, Abhay; Saroj, Usha; Kumar, Ravi; Singh, Satyendra Kumar; Choudhary, Anil K.; Farheen, Zobia; Priya, Shimpy

doi:10.7759/cureus.35919

Cited by 2 publications

(3 citation statements)

References 27 publications

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“…In oncology, ADRs significantly impact patient outcomes [23][24][25]. Studies on voluntarily reported ADRs involving anticancer drugs highlight the prevalence among 41-60year-olds, particularly female subjects, with skin issues and shivering as common symptoms associated with taxanes, targeted therapies, and platinum drugs [23]. Most of the ADRs were mild and preventable [23].…”

Section: Number Of Responsesmentioning

confidence: 99%

“…Studies on voluntarily reported ADRs involving anticancer drugs highlight the prevalence among 41-60year-olds, particularly female subjects, with skin issues and shivering as common symptoms associated with taxanes, targeted therapies, and platinum drugs [23]. Most of the ADRs were mild and preventable [23]. Another study reported that infections, nausea, and febrile neutropenia were frequent, involving drugs like platinum compounds and taxanes, with about 30.8% of reactions being preventable [24].…”

Section: Number Of Responsesmentioning

confidence: 99%

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Pharmacovigilance Practices by Healthcare Providers in Oncology: A Cross-Sectional Study

Alkofide,

Almalag,

Alromaih

et al. 2024

Pharmaceuticals

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Investigating pharmacovigilance (PV) practices among oncology healthcare providers (HCPs) is crucial for patient safety in oncology settings. This study aimed to assess the awareness, attitudes, and practices towards PV and identify barriers to effective adverse drug reaction (ADR) reporting for HCPs working in oncology-related settings. Employing a cross-sectional survey design, we collected data from 65 HCPs, focusing on their experiences with ADR reporting, education on ADR management, and familiarity with PV protocols. The results showed that about half of the responders were pharmacists. Around 58.9% of the respondents reported ADRs internally, and 76.9% had received some form of ADR-related education. However, only 38.5% were aware of formal ADR review procedures. Methotrexate and paclitaxel emerged as the drugs most frequently associated with ADRs. The complexity of cancer treatments was among the common reasons for the low reporting of ADRs by the study participants. The findings highlight the need for enhanced PV education and standardized reporting mechanisms to improve oncology care. We conclude that reinforcing PV training and streamlining ADR-reporting processes are critical to optimizing patient outcomes and safety in oncology, advocating for targeted educational interventions and the development of unified PV guidelines.

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Section: Number Of Responsesmentioning

confidence: 99%

Section: Number Of Responsesmentioning

confidence: 99%

Pharmacovigilance Practices by Healthcare Providers in Oncology: A Cross-Sectional Study

Alkofide,

Almalag,

Alromaih

et al. 2024

Pharmaceuticals

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“…19 According toMohammedin et al (2021), the age group most affected by stroke is the non-elderly group, aged 50-59 years (49%).…”

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confidence: 99%

The Relationship of D-dimer Levels and the Incident of Deep Vein Thrombosis in Acute Ischemic Stroke Patients at Haji Adam Malik General Hospital Medan

Gatot,

Syahrini Lubis

2023

Int J Res Rev

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Background: Deep Vein Thrombosis (DVT) is the formation of a thrombus in deep veins, often observed in stroke patients due to immobilization and infection during hospitalization. High D-dimer levels are associated with DVT in stroke patients. This study aims to evaluate the association between D-dimer levels as a diagnostic tool for DVT in acute ischemic stroke patients. Methods: This cross-sectional, retrospective study was conducted from May to August 2023. The study was carried out on acute ischemic stroke patients at Haji Adam Malik General Hospital, Medan, using consecutive sampling. Doppler ultrasound was used as the gold standard, and D-dimer data were analyzed using the SPSS program, employing the Chi-square test or Fisher's exact test. Results: Of the 49 patients, 35 met the inclusion criteria. Among the patients, 24 (68.6%) were male, 23 (65.7%) were over 50 years old, and 30 (85.7%) had a Body Mass Index (BMI) between 18-24.9. The mean D-dimer value was 2153.43 (±1506.88) ng/mL. All 21 (100%) DVT cases were asymptomatic. According to the Well's score, 15 patients scored 1 (42.8%), 20 patients (57.2%) scored 2, and the probability of DVT is in the moderate range for all 35 patients. The Fisher's Exact Test yielded a p-value of 0.028 (p<0.05). Conclusion: There is a significant relationship between D-dimer levels and the incidence of DVT in patients experiencing acute ischemic stroke. Keywords: Acute Ischemic Stroke, D-dimer, Deep Vein Thrombosis, Doppler Ultrasound

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A Study on the Clinical Profiles of Patients With Cerebrovascular Accident (Stroke) in a Tertiary Care Hospital in Jharkhand

Cited by 2 publications

References 27 publications

Pharmacovigilance Practices by Healthcare Providers in Oncology: A Cross-Sectional Study

Pharmacovigilance Practices by Healthcare Providers in Oncology: A Cross-Sectional Study

The Relationship of D-dimer Levels and the Incident of Deep Vein Thrombosis in Acute Ischemic Stroke Patients at Haji Adam Malik General Hospital Medan

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