A study on the characteristics of pollutant release and transfer registers (PRTRs) and cancer incidence rates in Korea

Im, JiYoung; Kim, Hyunji; Kim, Bo-Kyeong; Yun, Jeonghyeon; Lee, Jiho; Lee, ChungSoo

doi:10.1007/s11356-019-04868-x

Cited by 5 publications

(2 citation statements)

References 28 publications

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“…Rapid developments in technology, changing lifestyles, environmental pollution and chemicals cause negative impacts on human health and natural resources (Im et al, 2019). Therefore, people are exposed to many carcinogens and mutagenic substances of exogenous origin in their daily lives.…”

Section: Introductionmentioning

confidence: 99%

Protective Effects of Grape Molasses and Resveratrol Against DMBA Induced Oxidative Stress in Rat Ovarian Tissues

Kıran

Otlu

Karabulut

et al. 2019

Middle Black Sea Journal of Health Science

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The polyphenolic compound, resveratrol (3, 4', 5-trihydroxystilbene), trans-resveratrol is a natural phytoalexin that exists in many different foods such as grape peel and seed, peanut, mulberry and blueberry. Molasses is a natural food obtained by boiling and concentrating fruit juices known to be rich in minerals such as iron, phosphorus, potassium, sodium, calcium and magnesium, and phosphoric acid, formic acid, organic acids and some vitamins. Polyphenolic compounds are natural antioxidants and are known to have protective effects against tissue damage caused by reactive oxygen species (ROS). In this study, we aimed to investigate the protective effects of grape molasses and resveratrol on ovarian damage induced by 7, 12-dimethylbenz [a] anthracene (DMBA). Methods: A total of 42 old female Wistar Albino rats, aged 18 weeks were divided into six groups. 10 mg/kg DMBA was injected in the rats in DMBA group subcutaneously on day 0 and day 7 while grape molasses feed with 20% grape molasses was given along with DMBA application to the rats in DMBA + grape molasses group. Resveratrol was administered by subcutaneous injection at 10 mg/kg/day to the DMBA + Resveratrol group, while only feed with 20% grape molasses was given to the grape molasses group. Resveratrol was administered by subcutaneous injection at 10 mg/kg/day to the resveratrol group. Results: GSH activity between the control group and molasses group, DMBA and DMBA + molasses groups and the control group and the DMBA + grape molasses groups was found statistically significant. Regarding the NO activity, the difference between the DMBA and resveratrol groups, DMBA and DMBA + resveratrol groups and the grape molasses and resveratrol groups was found statistically significant. MDA activity between DMBA + resveratrol and DMBA + grape molasses groups, and DMBA + grape molasses and grape molasses groups was found statistically significant. Conclusion: Molasses as one of the most important nutrient sources of Eastern and Central Anatolia was observed to decrease ovarian tissue oxidative damage induced with DMBA compared to resveratrol.

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Section: Introductionmentioning

confidence: 99%

Protective Effects of Grape Molasses and Resveratrol Against DMBA Induced Oxidative Stress in Rat Ovarian Tissues

Kıran

Otlu

Karabulut

et al. 2019

Middle Black Sea Journal of Health Science

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“…These instruments obliged all facilities to declare all emissions above the designated thresholds of the E-PRTR, with this information then being used to create an inventory of geo-located facilities in Europe that have an environmental impact. This resource makes it possible to carry out analyses of the health impacts of residential proximity to polluting industrial facilities, such as the impact on cancer rates [9,10]. In 2001, in Europe, Spain was found to be the greatest emitter of almost one third of all E-PRTR-registered pollutant substances released into the air and among the three most contaminating countries for two-thirds of all such substances.…”

Section: Introductionmentioning

confidence: 99%

Cancer Mortality and Deprivation in the Proximity of Polluting Industrial Facilities in an Industrial Region of Spain

Santos-Sánchez

Córdoba-Doña

García‐Pérez

et al. 2020

IJERPH

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Residential proximity to industrial facilities that release pollutants is a source of exposure to a high number of toxics, many of them known or suspected carcinogens. The objective of the study was to analyze the association between lung, larynx, bladder, and kidney cancer mortality and deprivation in areas proximate to polluting industrial facilities in Cadiz, a highly industrialized province in Spain. An ecological study at census tract level was carried out to estimate the mortality rates associated with deprivation and proximity to polluting industrial facilities (1–5 km) using the Besag–York–Mollié model. The results show a negative social gradient for lung and larynx cancers in males and greater risk of lung cancer was observed in the least deprived areas in females. These associations were found regardless the distance to industrial facilities. Increasing excess risk (relative risk; 95% credibility interval) of lung cancer for males (1.09; 1.02–1.16 at 5 km vs 1.24; 1.08–1.41 at 1 km) and bladder cancer for males (1.11; 1.01–1.22 at 5 km vs 1.32; 1.08–1.60 at 1 km) and females (1.32; 1.04–1.69 at 4 km vs 1.91; 1.28–2.86 at 1 km) was found as proximity to polluting industrial facilities increased. For kidney cancer, high risks were observed near such facilities for both sexes. Knowing the possible influence of industrial pollution and social inequalities over cancer risk allows the definition of policies aimed at reducing the risk.

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A Study on the Characteristics of Hazardous Pollutant Emissions in Korea from 2007 to 2016

Kim

et al. 2020

Int J Environ Res

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A study on the characteristics of pollutant release and transfer registers (PRTRs) and cancer incidence rates in Korea

Cited by 5 publications

References 28 publications

Protective Effects of Grape Molasses and Resveratrol Against DMBA Induced Oxidative Stress in Rat Ovarian Tissues

Protective Effects of Grape Molasses and Resveratrol Against DMBA Induced Oxidative Stress in Rat Ovarian Tissues

Cancer Mortality and Deprivation in the Proximity of Polluting Industrial Facilities in an Industrial Region of Spain

A Study on the Characteristics of Hazardous Pollutant Emissions in Korea from 2007 to 2016

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