A study on the biodegradable novel chitosan nanofiber membrane as a possible tool for guided bone regeneration

Shin, Soo Young; Park, Ho-Nam; Kim, Kyoung-Hwa; Lee, Seung-Jin; Park, Yoon-Jeong; Ku, Young; Rhyu, In‐Chul; Han, Soo-Boo; Chung, Chong-Pyoung

doi:10.5051/jkape.2004.34.3.543

Cited by 1 publication

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“…Chitosan is a copolymer of N-acetyl-glucosamine and N-glucosamine are obtained from chitin, which is widely distributed in the natural world, such as the shells of crustacean such as crabs and shrimp, the epidermis and outer shells of insects such as locusts, and the cell walls of fungi such as mushrooms and yeast. It is a natural product-derived material that can be obtained from the natural world and has the advantage of being biodegradable and nontoxic (Shin et al, 2004). The Chitosan indicates higher oral absorption with various biological effects such as anti-microbial, anti-tumor and anti-oxidant effects (Aam et al, 2010;Chung et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Ameliorative Effect of Chitosan Complex on Miniature Pig Sperm Cryopreservation

Hong

Sim

Park

et al. 2018

J Anim Reprod Biotechnol

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Cryopreservation is mainly used for preservation of boar sperm. However, this method stresses the sperm by reactive oxygen species (ROS), and the conception rate and the litter size are not more efficient than the liquid preservation of spermatozoa. Therefore, we use chitosan which is a natural product derived antioxidant compound. We used GnHA (chitosan+hyaluronic acid) and GnHG (chitosan hydrogel) as chitosan complexes to cryopreserve boar sperm for improve sperm metabolism and function. Sperm parameter (sperm motility, progressive motility, path velocity, straight-line velocity, curvilinear velocity) is measured by computer-assisted sperm analysis (CASA) using frozen sperm with GnHA or GnHG (0, 0.25, 0.5, 1 mg/mL), respectively. Also, lipid peroxidation analysis using malondialdehyde (MDA) is performed to confirm the antioxidative effect of chitosan in frozen spermatozoa. CASA analysis showed GnHA and GnHG are effective against cryopreserved boar sperm. And antioxidant effect is measured by lipid peroxidation analysis. GnHA and GnHG, which is chitosan complex are effective for boar sperm cryopreservation by antioxidant effect.

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Section: Introductionmentioning

confidence: 99%