A Study on Renal Function Status of Patients with Hypothyroidism attending a Tertiary Care Hospital in North Bengal

Saha, Shubhrajit; Nath, Indrajit; Das, Mita; Mukherjee, Samarpita

doi:10.5005/jp-journals-10054-0046

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2022

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“…As in previous studies, TSH was directly correlated with creatinine and inversely correlated with GFR [25,26]. Moreover, FT4 was negatively correlated with creatinine and positively correlated with GFR.…”

Section: Discussionsupporting

confidence: 83%

“…A study on the relationship between thyroid dysfunction and serum creatinine found that among 191 hypothyroid patients, serum creatinine was negatively correlated with serum thyroxine (T4) (P<0.001) [ 27 ]. This may be because GFR is correlated with cardiac output and circulating blood volume, and this may be decreased due to impaired activity of the renin-angiotensin-aldosterone system in hypothyroid patients [ 25 ]. Furthermore, hypothyroidism may also increase creatinine release from muscles [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

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