A study on pregnancy induced hypertension and foetal outcome among patient with PIH at tertiary care hospital, Valsad

Patel, Ravikant; Baria, Hinal; Patel, Hinaben R.; Nayak, Sunil

doi:10.18203/2394-6040.ijcmph20174843

Cited by 17 publications

(30 citation statements)

References 11 publications

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“…Solange et al and Patel et al also reported most common age group was 20-34 year (64%) and [18][19][20][21][22][23][24][25][26] year (56%) respectively. 15,16 In present study, mean systolic blood pressure of pregnancy induced hypertensive patients was 148+3.8 mmHg and mean diastolic blood pressure was 95+1.4 mmHg. Similarly, Sachan et al in their study reported mean systolic blood pressure of 145.32±9.7 mmHg and mean diastolic pressure of 93.72±5.2 mmHg.…”

Section: Discussionsupporting

confidence: 45%

“…20 However, Patel et al found pain abdomen in 48.44% patients, vomiting in 18.75% and headache in 12.5% of the women with pregnancy induced hypertension. 16 In present study, most common complication was CNS symptom including seizure (Eclampsia) in 15% patients followed by vaginal bleeding (including abruption) in 13% and renal derangement in 4.4% patients. Other less common complications were pulmonary edema in 5.5% and HELLP syndrome in 2.2% patients.…”

Section: Discussionmentioning

confidence: 46%

“…20 Patel et al also reported that out of 64 PIH mother 54.69% had preterm delivery, 4.69% had post term delivery. 16 53.12% of babies are low birth weight, 07.81% are IUGR. Out of 64 delivery 12 (18.75%) of babies were required NICU admission for various causes.…”

Section: Discussionmentioning

confidence: 99%

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Biochemical parameter and feto-maternal outcome in preeclampsia: a hospital based observational study

Nagar¹,

Nagar²,

Gupta³

2018

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONPregnancy is a physiological phenomenon for most women. However, some develop problems during its evolution, putting both the mothers and the conceptus health at sake. Hypertensive disorders of pregnancy (HDPs) are one of the maternal diseases that cause detrimental effects on to the maternal, fetal, and neonatal health. The hypertensive disorders of pregnancy (HDPs) complicate about 3-10% of pregnancies. 1 They are one of the major contributors to maternal and fetal mortality and morbidity globally; maternal complications include eclampsia, stroke, and damage to the hepatic and renal organs etc. 2 Hypertension diseases during pregnancy includes pregnancy-induced hypertension (PIH) (without proteinúria), pre-eclampsia (with proteinuria), and eclampsia (pre-eclampsia with convulsions). Pregnancy termination reverses the clinical manifestations of the disease, suggesting that trophoblastic invasion has a central role in the pathogenesis of preeclampsia. 3 A recent study revealed that excessive placental secretion of soluble fms-like tyrosine kinase-1 may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. 3 In a multicenter study, approximately 30% of HDP cases were due to chronic hypertension, while 70% were due to gestational hypertension/preeclampsia. 4 ABSTRACT Background: Preeclampsia is one of the maternal diseases that cause detrimental effects on to the maternal, fetal, and neonatal health. The objective of the present study was to analyse maternal, perinatal outcome and investigation parameter in preeclampsia. Methods: This is an observational study and total of 90 consecutive patients were enrolled who has blood pressure ≥ 140/90 mmHg after 20 weeks of gestation with proteinuria (1+ by dipstick). Results: Among enrolled patients, 52 (58%) were in age group of 25-35 year and 51 (57%) were primigravida. Mean systolic and diastolic blood pressure of patients was 148±3.8 mm of Hg and 95±1.4 mm of Hg respectively. Most common presenting symptom was labor pain in 65 (72%) patients followed by edema in 61 (68%) patients. Most common complication was CNS symptom including seizure (Eclampsia) in 13 (15%) patients followed by vaginal bleeding (including abruption) in 12 (13%) patients. Mean hemoglobin level was 9.12±0.9 gm/dl. Mean urea and creatinine values were 34±4.6 mg/dl and 1.5±1.1 mg/dl respectively. Out of total 90 patients, 18 (20%) had elevated liver enzymes. Most common neonatal outcome was low birth weight 63 (70%) and 40 (44%) were preterm. APGAR score was less than 7 in 11 (12%) patients and more than 7 in 79 (88%) patients. Five (5.5%) newborn were still born. Conclusions: Preeclampsia is associated with multiple maternal and neonatal complications. Hence, there is a need for regular antenatal checkup to detect early and strengthening of neonatal intensive care units.

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Section: Discussionsupporting

confidence: 45%

Section: Discussionmentioning

confidence: 46%

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Biochemical parameter and feto-maternal outcome in preeclampsia: a hospital based observational study

Nagar¹,

Nagar²,

Gupta³

2018

Int J Reprod Contracept Obstet Gynecol

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“…Initiation of antihypertensive treatment at values ≥ 140/90 mmHg is recommended with gestational hypertension. [28][29]…”

Section: Discussionmentioning

confidence: 99%

Prevalence of pregnancy induced thyroid disorders, diabetes and hypertension in a tertiary care teaching hospital: an observational study

Mummalaneni¹,

Narasingarao

Myneni³

2019

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONPregnancy induced thyroid disorders, diabetes and hypertension are the common endocrine and cardiovascular disorders seen maternally either in early and late period of pregnancy. Maternal thyroid dysfunction contributes many risk factors which includes increase thyroglobulin levels, renal excretion of iodine due to increased rate of glomerular filtration, alterations in thyroid hormone peripheral metabolism and modifications in iodine transfer to placenta. 1 Iodine requirement increases by 50% during gestation period which can be compensate with synthesis and production of maternal thyroid hormones from gland and 10% increase in gland size is estimated. 2 Pregnancy is a stress factor for thyroid gland which resulting in hypothyroidism with dietary iodine deficiency and very limited thyroidal reserve women. Early pregnancy ABSTRACT Background: Pregnancy induced thyroid disorders, gestational diabetes mellitus (GDM) and gestational hypertension are common problems in women with gestational period. Published literate shows wide range of prevalence in pregnancy induced disorders in other states of India, and as of now the exact prevalence in our study population is not studied. Hence, there present study was aimed to know the prevalence of pregnancy induced disorders in pregnant women in South Indian population. Methods: A total of 120 subjects were followed-up at the time of recruitment to entire gestational period. Standard guidelines were followed for the assessment of thyroid hormone levels, glucose tolerance test (OGTT) and blood pressure values at different intervals and positions. Apart from detailed clinical history has been taken and routine basic and obstetrical investigations were done. Results: Prevalence of thyroid dysfunction (15.0%), gestational diabetes mellitus (11.7%) and gestational hypertension (9.2%) was reported in the present study population. Subclinical hypothyroidism was highest prevalence amount thyroid disorders. Gestational diabetes subjects have mean blood glucose levels of 230.68±17.48 mg/dL with OGTT test. Gestational hypertensive patients had SBP of 152.4±10.8 and DBP of 96.6±6.4; pre-hypertensive subjects had SBP of 134.2±5.48 and DBP of 6.8±4.6 respectively. Conclusions: Our study findings were slightly higher than normal prevalence's which are reported earlier by various authors. We suggested that early screening, diagnosis and treatment are warranted for the prevention of maternal and fetal complications in Indian population.

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“…6 Complication associated with hypertension in pregnancy for foetal, neonatal and maternal outcomes includes preterm birth, intra-uterine growth restriction, perinatal death, acute renal or hepatic failure, ante-partum or post-partum haemorrhages and maternal death. 7 Selection of antihypertensive drug therapy should depend upon the relative risk and benefits to the pregnant women. In pregnancy with blood pressure greater than 170/90mmhg has a greater risk of cerebrovascular accidents.…”

Section: Introductionmentioning

confidence: 99%

Drug utilization study of antihypertensive drugs used in the treatment of second and third trimester of pregnancy in tertiary care hospital

Lahamate

Razvi

Baig

et al. 2018

Int J Basic Clin Pharmacol

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Background: Hypertensive disorders are major cause of the perinatal and maternal mortality and morbidity worldwide. Aim of study was to evaluate current trend of antihypertensive drugs and to assess frequency and distribution of antihypertensive drugs in pregnancy.Methods: A retrospective observational study was conducted in a tertiary care hospital for period of six months in collaboration with department of obstetrics and gynaecology. Patients data recorded in case report form and analysed to study prescription pattern and related information.Results: Total of 104 cases were enrolled in this study. Prescribed antihypertensive drugs in pregnancy were Labetalol, Nifedipine, MgSO4 and furosemide. Most commonly prescribed drug was labetalol. In this study, Gestational hypertension was most common diagnosis in hypertensive disorder. Majority of drug prescribed from category C and A. In present study, Single drug therapy was most commonly prescribed for hypertension in pregnancy was 64.42% whereas multiple drug therapy was 35.57%. Most common maternal complication was anaemia i.e. 54.05% followed by placental abruption in 24.3%. Neonatal outcome was low birth weight i.e.36% followed by preterm birth i.e.24%.Conclusions: Labetalol found to be most common prescribed drug. Single drug therapy prescription was high as compared to multiple drug therapy prescription in hypertensive disorders in pregnancy. Gestational hypertension was most common cause of hypertensive disorder. Anaemia was found to be most common maternal complication encountered in hypertensive disorders in pregnancy. Most common adverse neonatal outcome was low birth weight.

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A study on pregnancy induced hypertension and foetal outcome among patient with PIH at tertiary care hospital, Valsad

Cited by 17 publications

References 11 publications

Biochemical parameter and feto-maternal outcome in preeclampsia: a hospital based observational study

Biochemical parameter and feto-maternal outcome in preeclampsia: a hospital based observational study

Prevalence of pregnancy induced thyroid disorders, diabetes and hypertension in a tertiary care teaching hospital: an observational study

Drug utilization study of antihypertensive drugs used in the treatment of second and third trimester of pregnancy in tertiary care hospital

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