Background: Cigarette smoking is common among the male collegiate population. It causes various negative effects on their body, particularly it affects the lungs. Hence, the aim of this study is to compare the aerobic and anaerobic capacities among the smoker and non-smoker male collegiate population. Methods: 68 healthy male college students participated in this study. Aerobic capacity was assessed by 3-minute step test. Anaerobic capacity was assessed by 30-meter sprint fatigue test. T-test was used to compare the data between groups. Result: Present study reported that smokers had a higher heart rate after performing 3-minute step test. The fatigue index was higher in smokers as compared to non-smokers. Conclusion: From the present study it can be concluded that cigarette smoking reduces the aerobic and anaerobic capacities of an individual.