A study on few biochemical parameters of clinically suspected and laboratory confirmed Leptospirosis cases

Zala, D. B.; Khan, Vikram; Das, Vincent

doi:10.31018/jans.v6i1.367

Cited by 4 publications

(3 citation statements)

References 6 publications

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“…The elevated SGOT and SGPT were encountered 100%, 89% in study by D. B. Zala, Vikram Khan and V. K. Das et al 10 The association between level of elevated SGOT, SGPT, total bilirubin, direct bilirubin and ALP at admission between survived patients and death patients among study subjects were found to be significant. This showed that those patients who died had raised levels of transaminase and bilirubin than those who survived.…”

Section: Discussionmentioning

confidence: 96%

Liver Function Test Abnormalities in Leptospirosis

Praveen¹,

Kumar²,

Radhakrishnan³

2018

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Section: Discussionmentioning

confidence: 96%

Liver Function Test Abnormalities in Leptospirosis

Praveen¹,

Kumar²,

Radhakrishnan³

2018

jebmh

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“…Nearly 160 mammalian species are the reservoirs and sources of infection, such as rodents, cattle, pigs, buffaloes, horses, sheep, goats, squirrels, bandicoots, and raccoons. (Zala et al 2014). This disease is caused by different serogroups that belong to the species Leptospira interrogans .…”

Section: Introductionmentioning

confidence: 98%

Leptospirosis in Ukraine (Lviv Oblast): Clinical and Epidemiological Features

Zubach

Telegina

Semenyshyn³

et al. 2019

Vector-Borne and Zoonotic Diseases

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The article describes the results of a retrospective analysis of medical records of 395 patients with a clinical diagnosis of leptospirosis treated at the Lviv Oblast Infectious Disease Clinical Hospital (Ukraine) between 2002 and 2016. The main risk factors for leptospirosis were contact with rodents or their excrements (26.84%) and bathing in ponds, small lakes, and reservoirs (10.63%). Among 276 patients in whom the anti-leptospira antibodies were detected by the microscopic agglutination test (MAT), the most common serotypes were Leptospira icterohaemorrhagiae (33.33%) and Leptospira grippotyphosa (25.0%). The mortality rate was significantly higher in patients where leptospirosis diagnosis was established based on clinical symptoms without confirmation by MAT (15.13% vs. 5.43%, p < 0.01).

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“…Leptospirosis is one of the six diseases enlisted by OIE with reference to "animal diseases and climate change" (19). The disease is most commonly found in rural and urban areas of tropical and subtropical parts of the world (30). It spreads more readily in tropical regions as Leptospira can survive longer in warm and humid environment.…”

Section: Introductionmentioning

confidence: 99%

Molecular characterisation of Leptospira strains in Pakistan

Sohail

Khan

Avais

et al. 2016

Journal of Veterinary Research

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Introduction: Leptospirosis affects a wide range of mammals, humans, and even a few poikilothermic animal species. In Pakistan, serological studies of equine leptospirosis have reported a prevalence of over 40%, but no study has ever been conducted towards molecular detection of Leptospira in horses. Material and Methods: Blood samples from 128 horses were screened using ELISA and 41 positive samples were examined for the presence of leptospiral DNA using specific primers for 16S rRNA gene. Results: Out of 41 tested samples, 20 samples were found to be PCR-positive, revealing a fragment of 306 bp after gel electrophoresis. Sequencing and phylogenetic analysis of positive samples revealed circulation of pathogenic Leptospira spp. in Pakistani horses. No evidence of circulation of intermediate species was found in this study. Conclusion: This study reports the first molecular evidence of equine leptospirosis in Pakistan and lays ground for further research in this area. It also confirms the efficiency of 16S rRNA for the diagnosis of equine leptospirosis.

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A study on few biochemical parameters of clinically suspected and laboratory confirmed Leptospirosis cases

Cited by 4 publications

References 6 publications

Liver Function Test Abnormalities in Leptospirosis

Liver Function Test Abnormalities in Leptospirosis

Leptospirosis in Ukraine (Lviv Oblast): Clinical and Epidemiological Features

Molecular characterisation of Leptospira strains in Pakistan

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