A Study on Electrolyte Changes in Neonates Receiving Phototherapy for Neonatal Hyperbilirubinaemia

Jena, Pradeep Kumar; Murmu, Mangal Charan; Bindhani, Tanusmita

doi:10.14260/jemds/2019/463

Cited by 5 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This decline was proposed to be due to reduced gastrointestinal absorption of sodium because of diarrhea and also generous frequent feeding ensured in our institution in these babies. Similar [17][18][19] results were recorded in other studies .…”

Section: Table 1: Baseline Characteristics Of Babies With Neonatal Ja...supporting

confidence: 91%

Effect of Phototherapy on Serum Electrolyte Levels in Neonatal Hyperbilirubinemia

Mahajan¹

2022

PIJR

View full text Add to dashboard Cite

Introduction: Neonatal hyperbilirubinemia is the most common clinical morbidity noted during the first seven days following birth. Amongst all the modalities available for management of neonatal hyperbilirubinemia, phototherapy is proven to be the safest. However, like any other intervention, phototherapy too has some of its own side effects. Aims & objective: This study aimed to investigate the effect of phototherapy on serum electrolyte levels in neonates admitted to neonatal intensive care unit with the diagnosis of neonatal hyperbilirubinemia. DemographicMaterial and methods: profiles, laboratory findings, and electrolyte levels before phototherapy and 48-72 hours after phototherapy of 290 patients hospitalized with neonatal hyperbilirubinemia between Sep 2020 and March 2022 were compared in this retrospective study. The mean sodium level significantly decreased from 141.3 mg/dL to 140.1 mg/dL afterResults: phototherapy. The decrease in potassium level was not statistically significant. The mean calcium level significantly decreased from 10.02 mg/dL to 9.68 mg/dL after receiving phototherapy. The level of serum electrolytesConclusion: in newborns may change with phototherapy. Serum sodium and calcium levels may decrease after phototherapy. For prevention of possible adverse effects, the changes in electrolyte levels should be considered in the clinical course of newborns receiving phototherapy and appropriate fluid-electrolyte treatments should be given

show abstract

Section: Table 1: Baseline Characteristics Of Babies With Neonatal Ja...supporting

confidence: 91%

Effect of Phototherapy on Serum Electrolyte Levels in Neonatal Hyperbilirubinemia

Mahajan¹

2022

PIJR

View full text Add to dashboard Cite

show abstract

“…The decrease in sodium and potassium levels were explained by Curtis M et al, [13] who stated that, phototherapy leads to significant impairment of water, potassium and sodium absorption. Also, Jena PK et al, [14] The etiology of hypocalcemia in infants treated with phototherapy is believed to be caused by increased urinary calcium excretion after exposure to phototherapy.…”

Section: Discussionmentioning

confidence: 99%

Effect of Phototherapy on Electrolytes, Liver and Kidney Functions During Treatment of Neonatal Hyperbilirubinemia. A Prospective-Analytical Study

Abohussein

Khalil²,

Fahmy

2022

Annals of Neonatology Journal

View full text Add to dashboard Cite

Background: Neonatal jaundice is a frequent problem affecting the newborn with various etiologies. Although phototherapy is considered the standard treatment for neonatal hyperbilirubinemia, it has some complications, as erythematous rashes, diarrhea, hyperthermia and electrolyte disturbance. Objective: To assess the effect of phototherapy on liver enzymes, renal functions, and serum electrolytes in jaundiced neonates before and after phototherapy and to assess changes in biochemical parameters according to mode of treatment including using Bilisphere then phototherapy, IVIG & Bilisphere then phototherapy and phototherapy only. Methods: One hundred neonates with unconjugated hyberbilirubinemia were enrolled. Jaundiced neonates were placed under phototherapy at a distance of 45-50 cm. Laboratory investigations were done before and after phototherapy. Results: Mean (± SD) TSB and DSB significantly declined after phototherapy with p value <0.001. Also, Mean (± SD) levels of AST and ALT showed statistically significant decrease after phototherapy (p<0.001). In addition, Mean (± SD) creatinine and urea levels showed statistically significant decrease after phototherapy (p<0.001).We also found statistically significant decrease in potassium and Calcium levels (p-value < 0.001) after treatment. As regards mode of treatment, we found a statistical significant decrease in TSB, creatinine and calcium among the different modes of treatment (p<0.001). Conclusion: Neonatal hyperbilirubinemia is considered a treatable condition and much of its ill-effects can be eliminated by proper intervention.However, continuous observation of electrolytes as potassium, sodium and calcium is needed as disturbance in their levels is of concern.

show abstract

Impact of phototherapy type and duration on serum electrolytes and blood glucose in neonatal hyperbilirubinemia: a prospective single-center cohort study

Tosson

Abdel-Razek

Yossif

et al. 2022

Egypt Pediatric Association Gaz

View full text Add to dashboard Cite

Background Neonatal hyperbilirubinemia (NH) is among the common neonatal morbidities. Phototherapy is its most used therapeutic intervention. Different delivering systems and types are currently available. This study aimed to detect and compare the effects of the different phototherapy types on serum electrolytes and blood glucose and to study the effect of phototherapy duration on them. Results Five hundred healthy newborns with indirect NH were treated by different phototherapy types (conventional, light emitting diode LED, intensive) according to severity and availability. Serum sodium (Na), potassium (K), calcium (Ca), blood urea nitrogen (BUN), creatinine (Cr), and blood glucose (Glu) were measured repeatedly over 48 h of phototherapy. In this prospective cohort study, 273 (54.6%) neonates were exposed to conventional phototherapy, 145 (29.0%) to LED, and 82 (16.4%) to intensive phototherapy. A highly significant negative correlation was found between phototherapy duration and serum levels of Na, K, Ca, BUN, and Cr (p < 0.001). There was a positive correlation between phototherapy duration and blood glucose level (p = 0.005). Each type of phototherapy individually significantly affected the Na, K, Bun, Cr, and Ca levels after 48 h. Comparing the effects of the 3 different phototherapy types together, no significant differences apart from a decline in potassium level at 48 h (p = 0.043) were recorded. Conclusions Serum electrolytes significantly decreased during phototherapy. These changes were affected by the phototherapy duration. The type of phototherapy had only some effect on serum potassium.

show abstract

A Study on Electrolyte Changes in Neonates Receiving Phototherapy for Neonatal Hyperbilirubinaemia

Cited by 5 publications

References 12 publications

Effect of Phototherapy on Serum Electrolyte Levels in Neonatal Hyperbilirubinemia

Effect of Phototherapy on Serum Electrolyte Levels in Neonatal Hyperbilirubinemia

Effect of Phototherapy on Electrolytes, Liver and Kidney Functions During Treatment of Neonatal Hyperbilirubinemia. A Prospective-Analytical Study

Impact of phototherapy type and duration on serum electrolytes and blood glucose in neonatal hyperbilirubinemia: a prospective single-center cohort study

Contact Info

Product

Resources

About