A study on conventional IMRT and RapidArc treatment planning techniques for head and neck cancers

Kumar, S.A. Syam; Nagarajan, Vivekanandan; Pothapregada, Sriram

doi:10.1016/j.rpor.2012.01.009

Cited by 23 publications

(6 citation statements)

References 20 publications

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“…Vieillot et al21 compared double arc with single arc VMAT (Rapid Arc) in anal canal cancer and found that double arc plans resulted in superior target coverage, dose homogeneity and conformity. Similar comparison study between single and double arc Rapid Arc plans was done by Kumar et al22 for head and neck cancers.…”

mentioning

confidence: 66%

Comparative dosimetric analysis of IMRT and VMAT (RapidArc) in brain, head and neck, breast and prostate malignancies

Ali

Babaiah

Madhusudhan

et al. 2014

Int J Cancer Ther Oncol

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Purpose: Intensity modulated radiotherapy (IMRT) in the recent past has established itself as a gold standard for organs at risk (OAR) sparing, target coverage and dose conformity. With the advent of a rotational treatment technology such as volumetric modulated arc therapy (VMAT), an inter-comparison is warranted to address the advantages and disadvantages of each technique. Methods: Twenty patients were selected retrospectively from our patient database. Sites included were brain, head and neck, chest wall, and prostate, with five patients for each site. For all the selected patients, both the IMRT and VMAT treatment plans were generated. Plan comparison was done in terms of OAR dose, dose homogeneity index (HI), dose conformity index (CI), target coverage, low isodose volumes, monitor units (MUs), and treatment time. Results: The VMAT showed better sparing of "parotids minus planning target volume (PTV)", spinal cord and head of femur as compared to the IMRT. The lung V40 for VMAT was lower, whereas the lung V10, contralateral lung mean dose, contralateral breast mean dose and mean body dose were lower with IMRT for chest wall cases. Both the VMAT and IMRT achieved comparable HI except for the brain site, where IMRT scored over VMAT. The CI achieved by the IMRT and VMAT were similar except for chest wall cases, whereas the VMAT achieved better dose conformity. The target coverage was comparable with both the plans. The VMAT clearly scored over IMRT in terms of average MUs (486 versus 812 respectively) and average treatment time (2.54 minutes versus 5.54 minutes) per treatment session. Conclusion: The VMAT (RapidArc) has a potential to generate treatment plans for various anatomical sites which are comparable with the corresponding IMRT plans in terms of OAR sparing and plan quality parameters. The VMAT significantly reduces treatment time as compared to the IMRT, thus VMAT can increase the throughput of a busy radiotherapy department.

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confidence: 66%

Comparative dosimetric analysis of IMRT and VMAT (RapidArc) in brain, head and neck, breast and prostate malignancies

Ali

Babaiah

Madhusudhan

et al. 2014

Int J Cancer Ther Oncol

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“…Therefore, RapidArc is presented by some authors as a fast and simple treatment modality, with precision that matches or exceeds dose conformity of the IMRT technique. 3,[7][8][9][10] However, unambiguous analysis should be done to point whether Rap-idArc plans are superior to the IMRT in respect to dosimetric parameters for a specific patient plan.…”

Section: Introductionmentioning

confidence: 99%

“…were specified in the literature to distinguish between plans. 11,12 The formulas of the indices mentioned before, are based mainly on simple rates of selected dosimetric parameters for target volume and healthy tissue. More appropriate analysis of dose distribution, which takes into account complex shape of the DVH curves and the priority of each structure, is very often impossible with available indices.…”

Section: Introductionmentioning

confidence: 99%

Comparison of dose distribution in IMRT and RapidArc technique in prostate radiotherapy

Leszczyński¹,

Ślosarek²,

Szlag³

2012

Reports of Practical Oncology & Radiotherapy

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“…The field of radiation medicine has experienced tremendous advancements over the last two decades including the development of state-of-the-art CT scanners for 3D imaging and powerful treatment planning systems [29]. Improved radiation delivery techniques such as IMRT and VMAT with image guidance are being increasingly evaluated in the clinical setting for patients with solid tumors including HNSCC [2][3][4][30][31][32]. Unfortunately, image-guided RT delivery methods are not routinely employed in preclinical studies.…”

Section: Discussionmentioning

confidence: 99%

“…Radiation therapy (RT) remains an important component of the standard of care for patients with head and neck squamous cell carcinomas (HNSCC). Clinical studies have shown that volumetric modulated arc therapy (VMAT) can ensure precise radiation delivery to tumors with reduced treatment times while sparing organs at risk (OAR) [1][2][3][4]. In VMAT, the radiation beam is continuously reshaped with changing intensity as it moves around the body to ensure highly conformal dose distribution to the target tissue while sparing surrounding tissues.…”

Section: Introductionmentioning

confidence: 99%

Development and Validation of a Clinically Relevant Workflow for MR-Guided Volumetric Arc Therapy in a Rabbit Model of Head and Neck Cancer

Bolookat

Malhotra

Rich

et al. 2020

Cancers

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There is increased interest in the use of magnetic resonance imaging (MRI) for guiding radiation therapy (RT) in the clinical setting. In this regard, preclinical studies can play an important role in understanding the added value of MRI in RT planning. In the present study, we developed and validated a clinically relevant integrated workflow for MRI-guided volumetric arc therapy (VMAT) in a VX2 rabbit neck tumor model of HNSCC. In addition to demonstrating safety and feasibility, we examined the therapeutic impact of MR-guided VMAT using a single high dose to obtain proof-of-concept and compared the response to conventional 2D-RT. Contrast-enhanced MRI (CE-MRI) provided excellent soft tissue contrast for accurate tumor segmentation for VMAT. Notably, MRI-guided RT enabled improved tumor targeting ability and minimal dose to organs at risk (OAR) compared to 2D-RT, which resulted in notable morbidity within a few weeks of RT. Our results highlight the value of integrating MRI into the workflow for VMAT for improved delineation of tumor anatomy and optimal treatment planning. The model combined with the multimodal imaging approach can serve as a valuable platform for the conduct of preclinical RT trials.

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A study on conventional IMRT and RapidArc treatment planning techniques for head and neck cancers

Abstract: RapidArc using double arc provided a significant sparing of OARs and healthy tissue without compromising target coverage compared to IMRT. The main disadvantage with IMRT observed was higher monitor units and longer treatment time.

Cited by 23 publications

References 20 publications

Comparative dosimetric analysis of IMRT and VMAT (RapidArc) in brain, head and neck, breast and prostate malignancies

Comparative dosimetric analysis of IMRT and VMAT (RapidArc) in brain, head and neck, breast and prostate malignancies

Comparison of dose distribution in IMRT and RapidArc technique in prostate radiotherapy

Development and Validation of a Clinically Relevant Workflow for MR-Guided Volumetric Arc Therapy in a Rabbit Model of Head and Neck Cancer

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