This study carried out in Ayadi Almostkbal Oncology Center-Alexandria, measurements carried on siemens linear accelerator (ARTISTE) which produces photons with energy 6 and 10 MV. This study aimed to dosimetric and verification measurements to apply step-and-shoot intensity modulated radiation therapy (IMRT) technique on patients. IMRT is a technology in radiation oncology that delivers radiation more precisely to the tumor while relatively sparing the surrounding normal tissues. Dosimetric measurements were carried out by using linear accelerator siemens (ARTISTE), PTW dosimetry system (relative and absolute) and slab solid phantom, using this tools we measure percentage depth dose, beam profile, flatness and symmetry. The measured data was collected and entered (transferred) to the treatment planning system CMS (XIO) for calculating dose distribution. These measurements were verified by comparing dose distribution came out planning system with dose distribution measured by PTW 2D-Array on linear accelerator. Dosimetry involves more than accounting for delivered dose. It involves ensuring that the MLC shapes are accurate and are correctly assigned to the patient. Any changes in shaping must be correctly and accurately incorporated into the field sequence. The information system should be implemented in a way that ensures good quality assurance practices.